Last update 22 Nov 2024

Imdusiran

Overview

Basic Info

Drug Type
siRNA
Synonyms
Imdusiran Sodium, AB 729, AB-729
+ [1]
Target
Mechanism
HBsAg inhibitors(HBsAg inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
AU
07 May 2021
Hepatitis B, ChronicPhase 2
BG
07 May 2021
Hepatitis B, ChronicPhase 2
CA
07 May 2021
Hepatitis B, ChronicPhase 2
NZ
07 May 2021
Hepatitis BIND Application
CN
10 May 2022
Hepatitis BIND Application
CN
10 May 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
22
Imdusiran, VTP-300, low-dose nivolumab
vdttkxewog(xfuqipbipz) = jkfnlygnia xopmfpxnsx (svivjthkzh )
Positive
15 Nov 2024
Phase 2
43
(A1: 24 wks IFN + 2 imdusiran doses + NA)
bafzacvhpo(nyffcelger) = tmweeqgech ntdrxhsibs (cvkqzcspzz )
Positive
01 Jun 2024
(A2: 24 wks IFN + NA)
bafzacvhpo(nyffcelger) = uyspategxq ntdrxhsibs (cvkqzcspzz )
Phase 2
40
imdusilan+VTP-300
fzamcdwtzk(uzlwkjjqvm) = There were no serious adverse events, Grade 3 or 4 adverse events or treatment discontinuations. toqvxvhyrx (tfrzchltdx )
Positive
09 Nov 2023
imdusilan+placebo
Phase 2
HBV RNA transcripts | HBV DNA | hepatitis B surface antigen (HBsAg)
-
otsixcbzxe(schimohgck) = qdvxnrqjyv cxbcxvpcql (weszuqzdsu )
Positive
25 Jun 2022
Control GalNAc siRNA
otsixcbzxe(schimohgck) = twmjpmvwtw cxbcxvpcql (weszuqzdsu )
Phase 2
27
pranwcrodu(qbunjkcuvu) = dlbilsmuxu cxuugkglnk (vprjklmpkx )
Positive
22 Jun 2022
Not Applicable
-
kqkwwbtphc(jxgsvnvggi) = xqjqwqeviu ysuvyjfmrp (plohhwvgiv )
-
23 Jun 2021
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Regulation

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