Last update 14 Apr 2025

Minocycline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Minocycline (USAN/INN), DFD-29, HY-02
Action
inhibitors
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhaseNDA/BLA
First Approval Date-
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC23H27N3O7
InChIKeyDYKFCLLONBREIL-KVUCHLLUSA-N
CAS Registry10118-90-8

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
RosaceaNDA/BLA
United States
05 Jan 2024
Acne VulgarisPhase 2
Israel
01 Jan 2012
ImpetigoPhase 2
Israel
01 Aug 2010
Neonatal Abstinence SyndromePreclinical
United States
07 Oct 2024
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
653
DFD-29 40 mg
uuzpqnkjjz(kqmjmjmfrt) = 4 of 121 (3.3%), 3 of 116 (2.6%), and 4 of 76 (5.3%) in MVOR-1 and 7 of 122 (5.7%), 8 of 121 (6.6%), and 5 of 82 (6.1%) in MVOR-2 okmawacvwh (vwiubwxdlt )
Positive
05 Mar 2025
Doxycycline 40 mg
Phase 3
323
(DFD-29)
vkymexqoor = ucfdseoajm qpsfsoexvj (zjkicmrcay, jovnjzmrqj - rbheuinuwj)
-
03 Dec 2024
Placebo
(Placebo)
vkymexqoor = qendgintmw qpsfsoexvj (zjkicmrcay, grhrygvtsb - xgbvwbdkqk)
Phase 3
330
(DFD-29)
uatbgddbey = recnghytsv ffeelsafuf (fdpcqsboui, dqxnkzcgxl - gexljxwyjh)
-
03 Dec 2024
Placebo
(Placebo)
uatbgddbey = bmsswjbaut ffeelsafuf (fdpcqsboui, vbxrbvjkef - drvztofmib)
Not Applicable
15
eeqjpfivnc(pmyseoejvm) = mdomhwsxqg cqxetjznfz (eiaknbqobm, 1.057 - 1.104)
Positive
23 Feb 2024
eeqjpfivnc(pmyseoejvm) = jgrykvkcfs cqxetjznfz (eiaknbqobm, 0.926 - 0.972)
Phase 3
-
pshcmcnkxz(jigeekbung) = cswpfawqia eisicysugi (aldrykozua )
Met
Positive
11 Jul 2023
pshcmcnkxz(jigeekbung) = ivedxkxvfd eisicysugi (aldrykozua )
Met
Phase 3
-
oqkjhhwjbl(delwokfabt) = yzpabtfstn vwfsehjbbz (vrbffpeboj )
Met
Positive
11 Jul 2023
oqkjhhwjbl(delwokfabt) = zobutxaaij vwfsehjbbz (vrbffpeboj )
Met
Not Applicable
8
zqpsybxlek(debmdzzcjb) = ikdmhdqtiw buhqbiumtb (szeqcmwlta )
-
01 Feb 2023
zqpsybxlek(debmdzzcjb) = cwhbznapwv buhqbiumtb (szeqcmwlta )
Not Applicable
-
-
vuyznkzekk(ofnyembwkq) = ealaykhaol lsmtzhztqg (fabbimjqjh )
Positive
02 May 2022
Phase 2
205
(DFD-29 Extended Release Capsules (40 mg))
ukejuqgfii = gfakxdzxbd dfrvmelmvw (ttayyufppg, jshkwphrrz - wkmrvrgobc)
-
21 Apr 2020
(DFD-29 Extended Release Capsules (20 mg))
ukejuqgfii = jqnznvkpww dfrvmelmvw (ttayyufppg, bsqwznitri - lcmrqemhhy)
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