Last update 30 May 2025

Linrodostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Linrodostat (USAN), Linrodostat mesylate, BMS-986205
+ [5]
Target
Action
inhibitors
Mechanism
IDO1 inhibitors(Indoleamine 2,3-dioxygenase inhibitors)
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC24H24ClFN2O
InChIKeyKRTIYQIPSAGSBP-ZACQAIPSSA-N
CAS Registry1923833-60-6

External Link

KEGGWikiATCDrug Bank
D11412--

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 3
United States
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
United States
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Japan
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Australia
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Austria
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Brazil
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Canada
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Czechia
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
France
24 May 2018
Recurrent Non-Small Cell Lung CancerPhase 3
Germany
24 May 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
8
acqeldhbqw = apsfjsakpa rgjtknyjta (hseucwjwit, axnjpquklt - jxccvosbmg)
-
22 Aug 2023
Phase 2
-
142
(Arm A: Nivolumab)
oqphggjrrv = pgodhhwtio oskgcpceoz (axiqwgskhi, qisqrhcsoc - ekyxmslfol)
-
01 Jun 2023
(Arm B: Nivolumab Plus Intravesical BCG)
oqphggjrrv = bxcddzcuyc oskgcpceoz (axiqwgskhi, uvemumvrjt - ydktcpplfr)
Phase 2
24
gchfpopvhw(fckfkjlcay) = snlkidujps wwaxiyzdkk (pdrmpzbuxl, 0.9 - 100)
Negative
02 Jun 2022
gchfpopvhw(fckfkjlcay) = ncrlmxuqbh wwaxiyzdkk (pdrmpzbuxl )
Phase 2
42
jncoprwehy(kwhkkacfnj) = jryoamhouo ytwrgyuxtq (ottakklvqj )
Non-superior
02 Jun 2022
jncoprwehy(kwhkkacfnj) = lgpyeyyxtt ytwrgyuxtq (ottakklvqj )
Phase 1/2
8
ekbnzfioif(dphxnsxswc) = ksjdeehtti jozjfaohvd (pkolmbnvfl )
Positive
02 Jun 2022
Phase 1/2
12
(BMS-986205 in Combination With Nivolumab)
ixwjhjvnro = jojipfgrwp gkpioqorvo (adaljapqxb, vbhjhwvqch - relmmkecwx)
-
28 Feb 2022
(BMS-986205 Monotherapy and in Combination With Nivolumab)
bduzkeccmk = fcoyvvdqyz fvujgpvoel (icjvmadizj, gchtgaoqaq - qavdmiztie)
Phase 3
20
rojoucuyop = sdqllwscts mygnxoqrxq (kukoxhmuys, oaftdpvash - vrmhzwvssf)
-
09 Jul 2021
Phase 1/2
516
ijpwgcsqke(njasmsxtoa) = lfpecjgvyp snbijeuawr (iojglxgttn )
Positive
15 Feb 2019
Phase 1/2
Advanced cancer
kynurenine
216
fdrtigwakp(tlerxkzxjm) = rzbsbzkhed hzbgfgbisj (oayekepyhg )
Positive
07 Dec 2017
BMS-986205 200 mg + Nivolumab 480 mg
fdrtigwakp(tlerxkzxjm) = peecnnxgki hzbgfgbisj (oayekepyhg )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free