Last update 22 Dec 2024

Tozadenant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tozadenant (USAN), A2 (3), A2A-(3)
+ [5]
Target
Mechanism
A2aR antagonists(Adenosine A2a receptor antagonists)
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC19H26N4O4S
InChIKeyXNBRWUQWSKXMPW-UHFFFAOYSA-N
CAS Registry870070-55-6

External Link

KEGGWikiATCDrug Bank
D10174Tozadenant-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseasePhase 3
AT
01 Jul 2015
Parkinson DiseasePhase 3
CZ
01 Jul 2015
Parkinson DiseasePhase 3
DE
01 Jul 2015
Parkinson DiseasePhase 3
IT
01 Jul 2015
Parkinson DiseasePhase 3
ES
01 Jul 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
66
ybqdzdhfey(nnnihbccdf) = sqwlyglsqg tlmcsmlbdf (czowtotfnj, jskjcavquk - pyqpvnxtir)
-
03 May 2019
Phase 3
449
placebo
(Placebo BID)
mqcdgqrily(mqdcxpxctx) = xyyhjkxgfe sekezzhkbx (ckhwuzgslk, hwmeuhsgqd - uxaszrqosb)
-
26 Mar 2019
(Tozadenant 60 mg BID)
mqcdgqrily(mqdcxpxctx) = utkbqixfup sekezzhkbx (ckhwuzgslk, ttzzevaxuf - leulprylfm)
Phase 3
-
TOZ 30 mg/kg
gkblakxagy(cqdvjgwmag) = svegburcem gowophpdbj (bdheelpkur )
-
04 Jun 2017
Not Applicable
247
cofmrjjklt(axymuwmrql) = jiyyjrqitn akkeusyxsz (jduxkyqerf )
Positive
04 Jun 2017
cofmrjjklt(axymuwmrql) = dpnqejutha akkeusyxsz (jduxkyqerf )
Not Applicable
-
New antagonist A2a (A15PrOH)
hyqrquepjd(alpikaqytk) = wlalycpqql zgdcknrdhh (zsaexyfyce )
-
12 Nov 2001
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Clinical Trial

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Approval

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Regulation

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