Drug Type Small molecule drug |
Synonyms (2E)-3-(1H-imidazol-4-yl)acrylic acid, (E)-3-(1H-imidazol-4-yl)-2-propenoic acid, Ci-UCA + [5] |
Target |
Mechanism IL-6 inhibitors(Interleukin-6 inhibitors), IL-8 inhibitors(Interleukin-8 inhibitors), JNK inhibitors(c-Jun N-terminal kinase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC6H6N2O2 |
InChIKeyLOIYMIARKYCTBW-UPHRSURJSA-N |
CAS Registry7699-35-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Plaque psoriasis | Phase 2 | FI | - | |
Xerophthalmia | Phase 2 | - | - | |
Dry Eye Syndromes | Discovery | US | 01 Dec 2014 | |
Moderate Atopic Dermatitis | Discovery | FI | 01 Mar 2011 | |
Severe Atopic Dermatitis | Discovery | FI | 01 Mar 2011 | |
Non-Muscle Invasive Bladder Neoplasms | Discovery | FI | 01 Oct 2009 | |
Cystitis, Interstitial | Discovery | FI | - |
NCT01320579 (Pubmed) Manual | Phase 2 | - | (psdqklvqbl) = Study treatments were well tolerated. hwqbkdhtpy (kyumzlynpg ) View more | Positive | 01 Jan 2014 | ||
Phase 2 | 42 | (luaczfqzsl) = ypwuqbhujb jveilrkxmz (sinqxlsdhl, 14 - infinity) View more | - | 20 Jun 2007 |