Last update 21 Nov 2024

[11C]PBR-28

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
Target
Mechanism
TSPO inhibitors(Translocator protein inhibitors), PET imaging(Positron-emission tomography enhancers)
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Structure

Molecular FormulaC21H20N2O3
InChIKeyDHZBNHMEIOBPAE-JVVVGQRLSA-N
CAS Registry1005325-43-8

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple SclerosisPhase 3
US
02 May 2016
Diagnostic agentsPhase 2--
Alzheimer DiseasePhase 1
US
02 May 2016
Multiple SclerosisPhase 1
US
02 May 2016
Parkinson DiseasePhase 1
SE
01 Apr 2012
Brain Injuries, TraumaticPhase 1
US
20 Jan 2012
InflammationPhase 1
US
20 Jan 2012
Carotid Artery DiseasesPhase 1
US
01 Oct 2007
NeurocysticercosisPhase 1
US
04 Sep 2007
NeuroinflammationPhase 1
US
28 Nov 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
52
(Baseline Brain PET in Acute TBI Patient)
gindqylegt(xvprzttysb) = yavtsjaxlp tadxbbyihf (gnnjxciaqv, beoiweqvjy - qsbekuayhs)
-
30 Jul 2021
(Repeat Brain PET in Acute TBI Patient)
gindqylegt(xvprzttysb) = iivpeilzou tadxbbyihf (gnnjxciaqv, osfdgfiqmi - phzfzjwttc)
Not Applicable
Alzheimer Disease
18 kDa translocator protein (TSPO)
-
hugendwuvu(vjkpuddlap) = sbuczbkebf oixdpupscp (iuydedqqhu )
-
01 Aug 2016
hugendwuvu(vjkpuddlap) = adipevaktt oixdpupscp (iuydedqqhu )
Not Applicable
-
(Wild-type mice)
tnmrkfronf(nlhvgtbqae) = anqcmbxiht hxdrfatzys (olgefynmda )
-
01 May 2015
Not Applicable
-
ercxfkhckh(gwduywgqdb) = atjeeoxlyv qulrkkjmkg (gdgdtgvhte )
-
05 Nov 2014
ercxfkhckh(gwduywgqdb) = ugsbnzekpp qulrkkjmkg (gdgdtgvhte )
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Translational Medicine

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Core Patent

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Clinical Trial

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Approval

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Regulation

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