Last update 04 Nov 2024

Fasudil mesylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fasudil, RT1968, 朗来
Mechanism
ROCK1 inhibitors(Rho-associated protein kinase 1 inhibitors), VDCCs blockers(Voltage-gated calcium channel blockers)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC15H21N3O5S2
InChIKeyMVCDPGYHRHUECK-UHFFFAOYSA-N
CAS Registry1001206-62-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Brain Ischemia
CN
15 May 2012
Vasospasm, Intracranial
CN
15 May 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Corticobasal degenerationPhase 2
US
22 Jan 2021
Supranuclear Palsy, ProgressivePhase 2
US
22 Jan 2021
DementiaPhase 2
US
15 Dec 2020
DementiaPhase 2
AU
15 Dec 2020
Amyotrophic Lateral SclerosisPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
17
(40 mg Fasudil)
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-
04 Nov 2014
(Placebo)
fchgfenkqb(zoqpbrnugp) = wzgrhqeptg gkgkzxmmme (awqwtgmvta, xzljslzwiv - zjfxmudvdu)
Not Applicable
5
gqppzbhfki(phujyxxiva) = ojpdqzvtuv meooueioqh (jcxsenyihz )
Positive
01 Jun 2013
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Regulation

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