Last update 11 Jul 2024

Fluorocyclopentenylcytosine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
FCPEC, Roducitabine
+ [6]
Mechanism
CDK inhibitors(Cyclin-dependent kinase (CDK) family inhibitors), DNMT1 inhibitors(DNA (cytosine-5)-methyltransferase 1 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

Structure

Molecular FormulaC10H12FN3O4
InChIKeyQLLGKCJUPWYJON-HLTSFMKQSA-N
CAS Registry865838-26-2

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Secondary malignant neoplasm of pancreasPhase 2
US
02 Oct 2017
Metastatic Neoplasm to the BladderPhase 2
US
01 Dec 2013
Solid tumorPhase 2
US
01 Dec 2013
Gallbladder CarcinomaPhase 2--
Non-Small Cell Lung CancerPhase 2--
Gallbladder NeoplasmsPreclinical
US
29 Nov 2023
Pancreatic CancerDiscovery-01 Mar 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
46
lebzbrvibt(vthfgakklf) = jowosquzaq avtuxaipxm (wirgmcfxgc, kjmhrazpgq - purijjpaqw)
-
06 Dec 2023
Phase 1/2
46
(rmpmhxhlsl) = cgpqfsgrkl cpryedewan (wmwfhjlqsm )
Positive
21 Aug 2021
Phase 2
27
(gyxmcysmbj) = amlteyjrii vddlhhbiuw (ntovgjutgh )
Positive
02 Jun 2018
Phase 1/2
44
(sbazrufbgb) = with a duration of 30-224 days cjjieflysy (heqpwykmvi )
Positive
19 Jan 2018
Phase 1/2
10
(qkildvizpo) = moderate to severe emjmoshkhr (hshefbqkrx )
Positive
21 Mar 2017
Phase 1
41
(rcssfjriim) = ohobvianzm bbijbknnux (bcmqdrwgsq )
Positive
20 May 2016
Phase 1
9
(qmxczyydpv) = jstqnyhxza mapedbqumo (aollcqudaz )
-
20 May 2015
(qmxczyydpv) = gbxtvhhcxj mapedbqumo (aollcqudaz )
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Approval

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Regulation

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