Last update 09 Apr 2025

PXL-770

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PXL 770
Target
Action
agonists
Mechanism
AMPK agonists(AMP activated protein kinase agonists)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC23H18ClNO3S
InChIKeyKPNBBJGVCJQHBR-UHFFFAOYSA-N
CAS Registry1523493-53-9

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AdrenoleukodystrophyPhase 2-01 Sep 2023
Nonalcoholic fatty liverPhase 2
United States
29 Mar 2019
Nonalcoholic SteatohepatitisPhase 1
United Kingdom
08 Mar 2021
Metabolic DiseasesPhase 1
United Kingdom
21 Aug 2017
Polycystic Kidney, Autosomal DominantPreclinical
France
18 Feb 2023
Diabetes Mellitus, Type 2Preclinical
France
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
PXL770 (150 mg/kg) for 90 days
ozolfldxvg(rzpvcbvoie) = pfcgjgtykd nczskxmhuv (oiscomobcp )
-
27 Aug 2021
PXL770 (150 mg/kg) for 7 days
ozolfldxvg(rzpvcbvoie) = opawkctoia nczskxmhuv (oiscomobcp )
Not Applicable
-
xcqosevsml(dppwnkqbnj) = oxngambfnt tlytsiuhpg (bstdssejax )
-
01 Jun 2021
Phase 1/2
120
rcvoldbxvc(tgiutjxxqa) = wgsbvvmgok eeebvzsoqa (datdpkxxkt, p=0.005 - p=0.03)
Positive
12 Mar 2021
rcvoldbxvc(tgiutjxxqa) = gnzixbzgfy eeebvzsoqa (datdpkxxkt, p=0.005 - p=0.03)
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Regulation

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