Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism AXL inhibitors(AXL receptor tyrosine kinase inhibitors), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC33H31F2N3O7 |
InChIKeyPCKYITPVOLEZKL-UHFFFAOYSA-N |
CAS Registry2222730-78-9 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Esophageal Squamous Cell Carcinoma | Phase 3 | CN | 26 Jan 2024 | |
Ewing Sarcoma | Phase 2 | CN | 05 Aug 2024 | |
Metastatic thymic carcinoma | Phase 2 | CN | 07 Feb 2023 | |
Recurrent Thymic Carcinoma | Phase 2 | CN | 07 Feb 2023 | |
Metastatic Solid Tumor | Phase 2 | CN | 17 May 2022 | |
Advanced Malignant Solid Neoplasm | Phase 1 | CN | 28 Aug 2020 | |
Advanced Lung Adenocarcinoma | IND Approval | CN | 11 Jan 2023 | |
Hematologic Neoplasms | Discovery | CN | 20 Nov 2019 |
NCT05260385 (ASCO2023) Manual | Phase 2 | 58 | (gyfbrhvxbg) = cgnkbygfmc jhubaizjes (hlozggchdp, 12.6 - 51.1) View more | Positive | 31 May 2023 | ||
Phase 1 | 41 | (lkquruwicm) = 60 mg QD opzaslfeja (bxvwiruvlr ) | Positive | 26 May 2023 | |||
Phase 1 | - | (vshmabwkfr) = Diarrhea (10.8%) dofojhievf (axhsorxcbq ) | Positive | 09 Jun 2022 |