Last update 02 Nov 2024

Cizutamig

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
CN-106, CND-106, CND106
+ [2]
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors), CD3 modulators(T cell surface glycoprotein CD3 modulators)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Plasma cell myeloma refractoryPhase 2
CN
20 May 2021
Plasma cell myeloma refractoryPhase 2
AU
20 May 2021
Relapse multiple myelomaPhase 2
CN
20 May 2021
Relapse multiple myelomaPhase 2
AU
20 May 2021
PemphigusIND Approval
CN
26 Apr 2024
Myasthenia GravisPreclinical
US
12 Sep 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
33
ljsuqkqcrv(rgfimveicj) = 在 0.2–120 mg 范围内,EMB-06显示出剂量比例增加的 PK 暴露,单次给药后的中位半衰期为 4.4 天。在剂量≥0.6 mg 时观察到 PD 活性。 nvsnwafddh (hnqlbaxmce )
Positive
04 Sep 2024
(≥120 mg)
Phase 1
33
apudqinrgo(hhnbszzxhk) = xiuhbzyblp wvffsiiuhk (zotfhtlfdo )
Positive
31 Oct 2023
apudqinrgo(hhnbszzxhk) = rfticdsnam wvffsiiuhk (zotfhtlfdo )
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Approval

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Regulation

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