Delving into the Latest Updates on Recombinant anti-human DR5 monoclonal antibody(Beijing Tongwei Shidai Shengwu Jishu Youxian Gongsi) with Synapse

Overview

Basic Info

Drug Type

Monoclonal antibody

Synonyms

Target

DR5

Action

agonists

Mechanism

DR5 agonists(Tumor necrosis factor receptor superfamily member 10B agonists)

Therapeutic Areas

Neoplasms

Active Indication

Advanced Malignant Solid Neoplasm

Inactive Indication-

Originator Organization

Beijing Cotimes Biotech Co., Ltd.

Active Organization

Beijing Cotimes Biotech Co., Ltd.

Lonn Ryonn PHARMA Ltd.

Inactive Organization

Sinotau Pharmaceutical Group

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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主要目的：探索重组抗人DR5单克隆抗体注射液单药治疗晚期实体肿瘤的安全性与耐受性；次要目的：评估重组抗人DR5单克隆抗体注射液单药治疗晚期实体肿瘤的药代动力学特征；初步评估重组抗人DR5单克隆抗体注射液治疗晚期实体肿瘤的抗肿瘤活性；评估重组抗人DR5单克隆抗体注射液的免疫原性；

[Translation]

Primary purpose: To explore the safety and tolerability of recombinant anti-human DR5 monoclonal antibody injection as a monotherapy for advanced solid tumors; Secondary purpose: To evaluate the pharmacokinetic characteristics of recombinant anti-human DR5 monoclonal antibody injection as a monotherapy for advanced solid tumors; To preliminarily evaluate the antitumor activity of recombinant anti-human DR5 monoclonal antibody injection in the treatment of advanced solid tumors; To evaluate the immunogenicity of recombinant anti-human DR5 monoclonal antibody injection;

Start Date25 Jul 2018

Sponsor / Collaborator

Lonn Ryonn PHARMA Ltd.

[+1]

100 Clinical Results associated with Recombinant anti-human DR5 monoclonal antibody(Beijing Tongwei Shidai Shengwu Jishu Youxian Gongsi)

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100 Translational Medicine associated with Recombinant anti-human DR5 monoclonal antibody(Beijing Tongwei Shidai Shengwu Jishu Youxian Gongsi)

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100 Patents (Medical) associated with Recombinant anti-human DR5 monoclonal antibody(Beijing Tongwei Shidai Shengwu Jishu Youxian Gongsi)

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100 Deals associated with Recombinant anti-human DR5 monoclonal antibody(Beijing Tongwei Shidai Shengwu Jishu Youxian Gongsi)

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Advanced Malignant Solid Neoplasm	Phase 1	China	Lonn Ryonn PHARMA Ltd.	25 Jul 2018
Advanced Malignant Solid Neoplasm	Phase 1	China	Beijing Cotimes Biotech Co., Ltd.	25 Jul 2018
Solid tumor	Discovery	China	Sinotau Pharmaceutical Group	25 Jul 2018

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Biosimilar

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