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Last update 20 Mar 2025
Diphenhydramine Hydrochloride/Ibuprofen
Last update 20 Mar 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Ibuprofen/Diphenhydramine Hydrochloride, 复方布洛芬缓释片(越洋医药) + [1] |
Target |
Action inhibitors, inverse agonists |
Mechanism COX inhibitors(Cyclooxygenases inhibitors), H1 receptor inverse agonists(Histamine H1 receptor inverse agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (21 Dec 2005), |
Regulation- |
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Structure/Sequence
Molecular FormulaC13H18O2 |
InChIKeyHEFNNWSXXWATRW-UHFFFAOYSA-N |
CAS Registry15687-27-1 |
View All Structures (2)
Related
2
Clinical Trials associated with Diphenhydramine Hydrochloride/IbuprofenCTR20222851
复方布洛芬多释片在健康受试者中的随机、开放、两周期、双交叉空腹状态下比较药代动力学试验。
[Translation] A randomized, open-label, two-period, double-crossover comparative pharmacokinetic study of ibuprofen extended-release compound tablets in healthy subjects under fasting conditions.
NCT05674721
A Randomized, Open Label, Single Center, Single Dose, Two Treatment, Two Period, Two Sequence Crossover Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) To Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions
100 Clinical Results associated with Diphenhydramine Hydrochloride/Ibuprofen
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100 Translational Medicine associated with Diphenhydramine Hydrochloride/Ibuprofen
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100 Patents (Medical) associated with Diphenhydramine Hydrochloride/Ibuprofen
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100 Deals associated with Diphenhydramine Hydrochloride/Ibuprofen
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R&D Status
Approved
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Sleep Initiation and Maintenance Disorders | United States | 21 Dec 2005 |
Developing
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Pain | Phase 1 | China | 28 Nov 2022 | |
| Sleep Initiation and Maintenance Disorders | Phase 1 | China | 28 Nov 2022 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1 | 77 | Advil PM Liqui-Gels+ibuprofen+diphenhydramine hydrochloride (Treatment A (Test)) | fythwzuhzr(ctpqsbrrtf) = ctwzbefofc dlmngzzxvq (fsxkidolkc, myysnpjylr - nezkrvfyix) View more | - | 23 Aug 2024 | ||
Advil PM Liqui-Gels+ibuprofen+diphenhydramine hydrochloride (Treatment B (Reference)) | fythwzuhzr(ctpqsbrrtf) = yrcnmscfyp dlmngzzxvq (fsxkidolkc, dzrnjdefoe - slqpaagegm) View more |
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