Drug Type Antibody drug conjugate (ADC) |
Synonyms Precem-TcT, M 9140, M9140 |
Target |
Action antagonists, inhibitors |
Mechanism CEACAM5 antagonists(Carcinoembryonic antigen related cell adhesion molecule 5 antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
metastatic non-small cell lung cancer | Phase 2 | United States | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | China | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Japan | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Australia | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Austria | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | France | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Germany | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Italy | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | South Korea | 03 Apr 2025 | |
metastatic non-small cell lung cancer | Phase 2 | Spain | 03 Apr 2025 |
Phase 1 | 40 | (Dose escalation (0.6-3.2 mg kg−1)) | aobxerrthk(sbndxmcbwj) = usgvwtimyp ilktkeyipz (wptgnzgdyk ) View more | Positive | 30 Jul 2025 | ||
Phase 1 | 60 | jwdsxdhbae(ietwigtyli) = dxlkimyawi clgnyfedos (krtqpsdugz ) View more | Positive | 30 May 2025 | |||
jwdsxdhbae(ietwigtyli) = owbusklctb clgnyfedos (krtqpsdugz ) View more | |||||||
NCT05464030 (ESMO2024) Manual | Phase 1 | 40 | jwzqpjboln(pljbvqrokj) = qczvytisai kfrqckqkhw (yspvafsmlm ) View more | Positive | 16 Sep 2024 | ||
jwzqpjboln(pljbvqrokj) = xcurfrrghy kfrqckqkhw (yspvafsmlm ) View more | |||||||
NCT05464030 (ASCO2024) Manual | Phase 1 | 40 | fdbaijbwcf(tqcceplpfn) = mnesdqmlvc ipzqbsvvwa (cilvqoasfo ) View more | Positive | 24 May 2024 |