Last update 16 May 2026

MLN-0415

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MLN 0415, MLN0415, SAR 479746
+ [1]
Target
IKKβ
Action
inhibitors
Mechanism
IKKβ inhibitors(inhibitor of nuclear factor kappa B kinase subunit beta inhibitors)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal DiseasesOther Diseases
Active Indication-
Inactive Indication
ArthritisInflammationRheumatoid Arthritis
Originator Organization
Millennium Pharmaceuticals, Inc.Millennium Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Takeda Pharmaceutical Co., Ltd.Takeda Pharmaceutical Co., Ltd.Millennium Pharmaceuticals, Inc.Millennium Pharmaceuticals, Inc.SanofiSanofi
License Organization
Millennium Pharmaceuticals, Inc.Millennium Pharmaceuticals, Inc.SanofiSanofi
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with MLN-0415
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100 Translational Medicine associated with MLN-0415
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100 Patents (Medical) associated with MLN-0415
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100 Deals associated with MLN-0415
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External Link

KEGGWikiATCDrug Bank
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DB05183

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ArthritisPhase 1
Japan
Takeda Pharmaceutical Co., Ltd.Takeda Pharmaceutical Co., Ltd.
-
InflammationPhase 1
Japan
Takeda Pharmaceutical Co., Ltd.Takeda Pharmaceutical Co., Ltd.
-
Rheumatoid ArthritisPhase 1-
Millennium Pharmaceuticals, Inc.Millennium Pharmaceuticals, Inc.
-
Rheumatoid ArthritisPhase 1-
SanofiSanofi
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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