Last update 20 Mar 2025

Ciclopirox

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone, Ciclopirox (USP/INN), Loprox cream
+ [5]
Target-
Action
inhibitors
Mechanism
Cell cycle inhibitors, DNA repair inhibitors, DNA synthesis inhibitors
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (30 Dec 1982),
RegulationOrphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC12H17NO2
InChIKeySCKYRAXSEDYPSA-UHFFFAOYSA-N
CAS Registry29342-05-0

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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Onychomycosis
Australia
22 May 2012
Dermatitis, Seborrheic
United States
28 Feb 2003
Candidiasis, Cutaneous
United States
30 Dec 1988
Candidiasis
United States
30 Dec 1982
Tinea corporis
United States
30 Dec 1982
tinea cruris
United States
30 Dec 1982
Tinea Pedis
United States
30 Dec 1982
Tinea Versicolor
United States
30 Dec 1982
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Porphyria, ErythropoieticPreclinical
Spain
19 Sep 2018
Porphyria, ErythropoieticPreclinical
Spain
19 Sep 2018
HIV InfectionsPreclinical
United States
01 Jan 2014
HIV InfectionsPreclinical
Canada
01 Jan 2014
LymphangiectasisPreclinical
United States
15 Apr 2011
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Clinical Result

Indication
Phase
Evaluation
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Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Regulation

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