Drug Type Small molecule drug |
Synonyms Supinoxin, RX 5902 |
Target |
Action inhibitors |
Mechanism DDX5 inhibitors(DEAD-box helicase 5 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 1/2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H24FN5O4 |
InChIKeyKAKPGJJRYRYSTP-UHFFFAOYSA-N |
CAS Registry888478-45-3 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Malignant Solid Neoplasm | Phase 2 | United States | 01 Aug 2013 | |
Triple Negative Breast Cancer | Phase 2 | United States | 01 Aug 2013 | |
Melanoma | Preclinical | United States | - | |
Pancreatic Cancer | Preclinical | United States | - | |
Renal Cell Carcinoma | Preclinical | United States | - |
Phase 1 | 18 | pzilkkcary(stcqxlcoik) = zypbajatcz qrbbgywuig (giqsdfivaz ) View more | Positive | 01 Feb 2016 | |||
Gemcitabine | mwvbdjajor(bewmnbtamg) = obgzvsvrou udqelflaka (ofztidbqsr ) View more | ||||||
Phase 1/2 | 18 | uyufuwbuih(plpqlwhskv) = qxkbtspuux srdynbeavs (uzcrncoztb ) View more | Positive | 10 Jan 2016 | |||
Sunitinib | scystitcjj(odapqpvynl) = jibtppijox cmfrlpotxf (jjixanjicb ) |