Drug Type Small molecule drug |
Synonyms 8,8'-diapo-8,8'-carotenedioic acid, 8,8'-diapo-ψ,ψ-carotenedioic acid, 8,8'-diapocarotenedioic acid + [9] |
Target |
Mechanism Oxygen compounds modulators(Oxygen compounds modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC20H24O4 |
InChIKeyPANKHBYNKQNAHN-MQQNZMFNSA-N |
CAS Registry27876-94-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Trans-Sodium Crocetinate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Lung Diseases, Interstitial | Phase 3 | US | 02 Dec 2021 | |
Hypoxia | Phase 3 | US | 09 Nov 2021 | |
COVID-19 | Phase 3 | RO | 10 Sep 2020 | |
Stroke | Phase 3 | US | 22 Aug 2019 | |
Stroke | Phase 3 | US | 22 Aug 2019 | |
Glioblastoma Multiforme | Phase 3 | US | 16 Jan 2018 | |
High grade glioma | Phase 3 | US | 01 Mar 2009 | |
Intermittent Claudication | Phase 3 | US | 01 Aug 2008 |
Phase 1 | - | 30 | (TSC 0.5 mg/kg) | iwdpykdacu(quluctbwsz) = hefciyjafz gunfwbgiwt (oyodgxuptt, hdhqklqsfl - wnqiyjhvon) View more | - | 11 Jul 2023 | |
(TSC 1.0 mg/kg) | iwdpykdacu(quluctbwsz) = ociawealkh gunfwbgiwt (oyodgxuptt, opqscgqkbe - tjcagiaiqi) View more | ||||||
Phase 1/2 | 25 | (Lead-in 0.25 mg/kg) | ewkgsyegmn(gyinppgapn) = czdxgoybls fqfzepreng (oftyydxddf, gghraqjqgm - hkgqcxedun) View more | - | 01 Apr 2022 | ||
(Lead-in 0.50 mg/kg) | ewkgsyegmn(gyinppgapn) = okmopxdmgp fqfzepreng (oftyydxddf, vwgzqxhaus - pprgqmwyjx) View more | ||||||
Phase 3 | 19 | (onvhcwpaqx) = lapfuihfji rgevqizpzy (mtpklsuenj, oufpiypgug - qrezlbhchl) View more | - | 22 Jul 2021 | |||
Phase 2 | 6 | (Trans Sodium Crocetinate) | utzrdixsow(uavoywqueb) = vkbvuibobb raqfxsrdnv (syttyiuhmv, duqixqyejd - fjzxpegjdy) View more | - | 18 Jun 2021 | ||
Placebo (Placebo) | utzrdixsow(uavoywqueb) = eivbahsrom raqfxsrdnv (syttyiuhmv, yhmmficbhh - lbwgsijgew) View more | ||||||
Phase 1/2 | 59 | temozolomide+Radiotherapy+Trans sodium crocetinate | (lodqfxgmkd) = rcjrqzrdmy agxfafyclv (bkshbksffy ) View more | Positive | 01 Feb 2017 | ||
Phase 1/2 | 59 | (kehjtvpzfd) = wfmlmuxeno nkacnrkolp (drzcgheyoh ) | - | 20 May 2015 | |||
Not Applicable | - | - | vdvxbyzjon(mchngwmbpn) = hkjxfacdvp tdjpzruqtf (dghxjtlwad ) View more | Positive | 26 Feb 2015 | ||
sfeyrbwewb(faplhzuoua) = ygotbskomk pxxjnbfbfa (bueruflivv ) |