Last update 31 May 2025

ION-269

Overview

Basic Info

Drug Type
ASO
Synonyms
ION-269
Target
APP
Action
inhibitors
Mechanism
APP inhibitors(Beta amyloid A4 protein inhibitors)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersOther Diseases
Active Indication
Alzheimer DiseaseDown Syndrome
Inactive Indication-
Originator Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
Active Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with ION-269
NCT06673069
/ RecruitingPhase 1
A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacokinetics of ION269 in Adults With Down Syndrome (Hero Study)
100 Clinical Results associated with ION-269
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100 Translational Medicine associated with ION-269
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100 Patents (Medical) associated with ION-269
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100 Deals associated with ION-269
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 1
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
20 Dec 2024
Alzheimer DiseasePhase 1
Spain
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
20 Dec 2024
Down SyndromePhase 1
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
20 Dec 2024
Down SyndromePhase 1
Spain
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
20 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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