Irritable bowel syndrome (IBS) is a gastrointestinal transit disorder characterized by chronic abdominal pain and impaired transit in the absence of demonstrated organic disease. Considered a non-fatal disease, its effects relate more to quality of life, work production and health care systems.
Given the complexity of this disease, no treatment has been recognized as standard treatment. The treatment is rather focused on treating the symptoms caused (chronic pain or intestinal transit disorder). In general, therapy is considered individualized and includes lifestyle/diet modifications and pharmaceutical therapy.
Several published case studies evaluating the effect of mesotherapy on improving the severity of the disease have demonstrated an improvement in the symptoms of this syndrome. Due to the limited number of case studies and the insufficient level of evidence to conclude, our study will therefore be a before-and-after intervention study, to evaluate the effect of four mesotherapy sessions on the treatment of IBS symptoms.

Start Date28 Feb 2024

Sponsor / Collaborator

Polyclinique de l'Europe SASU

CTRI/2022/12/047988

/ Not yet recruitingNot ApplicableIIT

Evaluating Pre-Emptive Analgesia of Etoricoxib, Thiocolchicoside and Dexamethasone in Lower Third Molar Surgery A Randomised Controlled Trail

Start Date11 Dec 2022

Sponsor / Collaborator-

CTRI/2022/07/043690

/ RecruitingPhase 4

A Prospective, Randomized, Parallel Group, Open Label, Multi-centric, Active Controlled Study to Evaluate the Efficacy and Safety of fixed dose combination of Etoricoxib(60mg) and Thiocolchicoside (4mg) vs Chlorzoxazone(500mg) and Diclofenac(50mg) and Paracetamol(325mg) in Low Back Pain.

Start Date06 Jul 2022

Sponsor / Collaborator

Mankind Pharma Ltd.

100 Clinical Results associated with Thiocolchicoside

100 Translational Medicine associated with Thiocolchicoside

100 Patents (Medical) associated with Thiocolchicoside

741

Literatures (Medical) associated with Thiocolchicoside

01 Dec 2025·SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Enhanced binding of triclocarban to catalase induced by coexisting nanoplastics

Article

Author: Lan, Jing ; Shi, Rongguang ; Zhao, Zongshan ; Li, Yaru ; Wang, Yaoyao ; Lou, Qi ; Zong, Wansong ; Guan, Rui

Triclocarban (TCC), as an emerging environmental contaminant, can induce changes of catalase (CAT) activities and the oxidative stress. Nanoplastics have also been found to readily bind to functional proteins and affect their physiological expressions. However, their combined toxicities are still not clearly illustrated at molecule level. Here, we explored the impact of polystyrene nanoplastics (PSNPs) on the binding of TCC to CAT, using a combination of spectroscopy, enzyme activity assays, dynamic light scattering analysis and molecular docking. The results show that CAT activity was overactivated and increased to 131 % and 138 % (TCC = 6 μM) by TCC alone and NPs-TCC exposure, respectively. Dynamic light scattering analysis demonstrate that CAT was adsorbed on the surface of PSNPs and formed a protein corona. Fluorescence, UV-visible and circular dichroism spectra analyses reveal that loosening of the CAT backbone and the reduction in α-helix content induced by TCC was further exacerbated by PSNPs. This structural perturbation may enhance the binding affinity of TCC to CAT. The coexistence of PSNPs and TCC could further increase CAT activity compared to individual TCC, probably being attributed to protein corona formation and enhanced conformational changes of CAT induced by PSNPs. These findings will contribute to the understanding of the oxidative damage in the co-existence of TCC and PSNPs, and provide new insights into the toxic effects in coexisting scenarios.

01 Nov 2025·BIORESOURCE TECHNOLOGY

Triclocarban removal in agricultural runoff using biochar-microbe-augmented bioretention drainage systems: Performance and role of microbial community

Article

Author: Charanaipayuk, Nampetch ; Sonsuphab, Khuanchanok ; Ratpukdi, Thunyalux ; Mhuantong, Wuttichai ; Saisuwan, Wannasorn ; Ngernyen, Yuvarat ; Siripattanakul-Ratpukdi, Sumana ; Jenjaiwit, Supitchaya

Triclocarban (TCC) is a widely used antimicrobial agent and has been detected as an environmental contaminant in agricultural areas. We aimed to remediate TCC-contaminated agricultural runoff using a bioretention drainage ditch system augmented with biochar (BC), free cells (FC), and biochar-immobilized cells (IC). In a batch test, FC achieved the highest removal efficiency (83 %), followed by IC (62 %) and BC (58 %). In a long-term system, IC and FC exhibited comparable TCC removal efficiencies (33-35 %), whereas BC removed TCC only 20 %. The TCC reduction was achieved through biodegradation as well as adsorption by biochar and extracellular polymeric substances (EPS). The adaptive responses of the microbes to TCC toxicity included cell shrinkage and appendage formation. Comamonas and potentially Alcaligenes contributed to the TCC degradation. Azospira and Flavobacterium were likely involved in EPS production. Overall, our findings suggest that biochar-microbe-augmented bioretention drainage ditch systems hold promise for cleaning up contaminated agricultural runoff.

01 Nov 2025·ENVIRONMENTAL RESEARCH

Microbial degradation and bioremediation of chlorinated aromatic emerging contaminants in the water environment: Advances and perspectives

Review

Author: Ren, Hao ; Yin, Yiran ; French, Christopher E ; Lu, Zhenmei

Emerging contaminants, especially chlorinated aromatic contaminants, are of growing concern due to their persistence in aquatic environments and the significant risks they pose to both aquatic ecosystems and human health. These pollutants resist conventional water treatment techniques, creating challenges for their removal. Microbial bioremediation, which utilizes the natural metabolic pathways of microorganisms, offers a promising and sustainable solution to mitigate their impact. This review focuses on three extensively studied chlorinated aromatic contaminants (chloramphenicol (CAP), triclosan (TCS), and triclocarban (TCC)) as case studies, providing a comprehensive analysis of their microbial degradation mechanisms. These compounds were selected based on their structural similarities, widespread environmental occurrence, and common effects on microbial ecosystems. This review highlights key metabolic pathways involved in the microbial degradation of these compounds, with a focus on their biochemical processes. It also examines various bioremediation strategies, including bioaugmentation, microbial fuel cells, and integrated approaches combining microorganisms with nanoscale materials or plants. Despite progress in understanding microbial degradation, critical aspects of the metabolic pathways remain insufficiently characterized. The enzymes and pathways involved in the degradation of CAP, TCS, and TCC are not yet fully elucidated, limiting the effectiveness of current bioremediation strategies. To overcome these knowledge gaps, we advocate for a deeper exploration of microbial enzymatic pathways, particularly microbial dechlorination, and the development of integrated, multi-technique bioremediation systems. Such innovative approaches could enhance the efficiency and scalability of bioremediation, providing effective solutions for managing these emerging contaminants.

News (Medical) associated with Thiocolchicoside

30 Nov 2024

·pharma.economictimes.indiatimes.com

Case against hosp for overpriced meds

Hyderabad: The Drug Control Administration (DCA) Telangana found a multi-speciality hospital in Malakpet charging patients 10 times more for medicines. DCA officials conducted a raid on the hospital. The medicines sold at exorbitant prices included IV injections, Avil injection (Pheniramine Maleate Injection), which is used to treat allergic conditions, and Zofer injection (Ondansetron injection), which is used to treat and prevent nausea and vomiting. Sales bills of drugs sold by the hospital located in Judges Colony, Malakpet, at higher prices were seized, and a case was registered against the hospital under the Essential Commodities Act , 1955, read with the Drugs (Prices Control) Order, 2013. The Zofer injection, which costs 13.35, was billed at 150. The NSL 100 IV fluid, which costs 22, was billed at 180. IV sets, which are used to administer medications to a patient through intravenous (IV) route, and Spafast-D injection (Thiocolchicoside + Diclofenac Injection), which is used to relieve pain, were among the highly overpriced medicines sold. "Action will be taken as per the law against all the offenders. According to the Drugs (Prices Control) Order, 2013, no person shall sell any medicine to a consumer at a price exceeding the price indicated on the label of the medicine pack," said VB Kamalasan Reddy, director general, DCA Telangana.

23 Aug 2024

·pharma.economictimes.indiatimes.com

Govt bans 156 medicines including antibiotics, painkillers, multivitamins: Here is the full list

New Delhi: In a significant move aimed at safeguarding public health, the Indian government has banned 156 fixed-dose combination (FDC) drugs, including a variety of antibiotics, painkillers, multivitamins, and medications for treating fever and hypertension. This decision marks the largest crackdown on FDCs since 2016, when 344 such drugs were prohibited. The Union Ministry of Health and Family Welfare issued a gazette notification on Thursday, officially prohibiting the manufacture, sale, and distribution of the banned FDCs. The ban was based on the recommendations of an expert panel that reviewed a total of 324 FDCs. Impact on Pharmaceutical Industry The banned FDCs include popular combinations such as mefenamic acid and paracetamol injections, commonly used for pain relief and fever, and omeprazole magnesium with dicyclomine HCl, used to treat abdominal pain. The ban is expected to impact major pharmaceutical companies, including Sun Pharmaceuticals, Cipla, Dr. Reddy's Laboratories, Torrent Pharmaceuticals, and Alkem Laboratories. Fixed Dose Combinations Drug Banned List Here is a table listing all 156 banned Fixed Dose Combinations (FDCs) SN Fixed Dose Combination (FDC) 1 Amylase + Protease + Glucoamylase + Pectinase + Alpha Galactosidase + Lactase + Beta-Gluconase + Cellulase + Lipase + Bromelain + Xylanase + Hemicellulase + Malt diastase + Invertase + Papain 2 Antimony Potassium Tartrate + Dried Ferrous Sulphate 3 Benfotiamine + Silymarin + L-Ornithine L-aspartate + Sodium Selenite + Folic acid + Pyridoxine hydrochloride 4 Bismuth Ammonium Citrate + Papain 5 Cyproheptadine HCl + Thiamine HCl + Riboflavine + Pyridoxine HCl + Niacinamide 6 Cyproheptadine Hydrochloride + Tricholine Citrate + Thiamine Hydrochloride + Riboflavine + Pyridoxine Hydrochloride 7 Rabeprazole Sodium (As enteric coated tablet) + Clidinium Bromide + Dicyclomine HCl + Chlordiazepoxide 8 Fungal Diastase + Papain + Nux vomica Tincture + Cardamom Tincture + Casein Hydrolysed + Alcohol 9 Mefenamic Acid + Paracetamol Injection 10 Omeprazole Magnesium + Dicyclomine HCl 11 S-adenosyl methionine + Metadoxine + Ursodeoxycholicacid BP + L-Methylfolate Calcium eq. to L- Methylfolate + Choline bitartratee + Silymarin + L-ornithine Laspartate + Inositol + Taurine 12 Silymarin + Thiamine Mononitrate + Riboflavin + Pyridoxine HCl + Niacinamide + Calcium pantothenate + Vitamin B12 13 Silymarin + Pyridoxine HCl + Cyanocobalamin + Niacinamide + Folic Acid 14 Silymarin + Vitamin B6 + Vitamin B12 + Niacinamide + Folic acid + Tricholine Citrate 15 Sodium Citrate + Citric Acid Monohydrate Flavored with Cardamom Oil, Caraway Oil, Cinnamon Oil, Clove Oil, Ginger Oil + Alcohol 16 Sucralfate + Acelofenac 17 Sucralfate + Domperidone + Dimethicone 18 Sucralfate + Domperidone 19 Tincture Ipecacuanha + Tincture Urgenia + Camphorated Opium Tincture + Aromatic Spirit of Ammonia + Chloroform + Alcohol 20 Ursodeoxycholic Acid + Metformin HCl 21 Weak Ginger tincture + Aromatic Spirit of Ammonia + Peppermint Spirit + Chloroform + Sodium Bicarbonate + Compound Cardamom + Alcohol 22 Sucralfate + Pantoprazole Sodium + Zinc Gluconate + Light Magnesium Carbonate 23 Aloe + Vitamin E Soap 24 Povidone Iodine+ Metronidazole + Aloe 25 Azelaic acid + Tea Tree Oil + Salicylic acid + Allantoin + Zinc oxide + Aloe vera + Jojoba oil + Vitamin E + Soap noodles 26 Azithromycin + Adapalene 27 Calamine + Aloes + Allantoin 28 Calamine + Diphenhydramine Hydrochloride + Aloe + Glycerine + Camphor 29 Chlorphenesin + Zinc oxide + Starch 30 Clindamycin Phosphate + Zinc acetate 31 Gamma Benzene Hexachloride + Benzocaine 32 Glucosamine hydrochloride + Diacerein + Menthol + Camphor + Capsaicin 33 Hydroxyquinone 2.0%w/w + Octyl Methoxycinnamate 5.0% w/w + Oxybenzone 30 % w/w 34 Ketoconazole +Zinc Pyrithione +D-Panthenol +Tea Tree Oil +Aloes 35 Ketoconazole +Aloe vera+ Vitamin A Acetate 36 Ketoconazole +Aloes + ZPTO 37 Kojic Acid +Arbutin +Octinoxate +Vitamin E + Mulberry 38 Lornoxicam +capsaicin +menthol+ camphor 39 Lornoxicam + Thiocolchicoside +Oleum Lini +Menthol + Methyl salicylate 40 Menthol + Aloe vera Topical Spray 41 Menthol +Lignocaine HCl +Aloe vera gel +Clotrimazole +Diphenhydramine 42 Miconazole nitrate + Gentamicin + Fluocinolone Acetonide +Zinc Sulphate 43 Miconazole +Tinidazole 44 Minoxidil +Aminexil+ Alcohol 45 Minoxidil +Azelaic acid + saw palmetto 46 Minoxidil +Aminexil 47 Pine Bark extract+ Kojic acid +Sodium Ascorbyl Phosphate 48 Povidone Iodine +Tinidazole +Zinc sulphate 49 Povidone Iodine + Ornidazole + Dexpanthenol 50 Salicyclic acid +Aloe vera+ Allantoin +D-Panthenol 51 Silver sulphadiazine +Chlorhexidine Gluconate solution +Allantoin + Aloe vera gel +Vitamin E acetate 52 Sodium salicylate + Zinc gluconate + Pyridoxine HCl 53 Tetracycline + Colistin Sulphate 54 Clomiphene +Ubidecarenone 55 Combikit of Clomiphene Citrate + Estradiol Valerate 56 Flavoxate HCl +Ofloxacin 57 Clomiphene Citrate +N-Acetylcysteine 58 Primerose Oil +Cod liver oil 59 Sildenafil Citrate +Papaverine +L-Arginine 60 Tranexamic acid +Mefenamic acid + Vitamin K1 61 Divalproex Sodium +Oxcarbazepine 62 Divalproex Sodium + Levetiracitam 63 Ergotamine tartrate +Caffeine + Paracetamol +Prochlorperazine maleate 64 Piracetam + Ginkgo biloba extracts + Vinpocetin 65 Ginkgo biloba + methylcobalamin 66 Ginkgo biloba + methylcobalamin + Alpha lipoic acid +Pyridoxine HCl 67 Ginseng Extract +Dried extract of Ginkgo Biloba 68 Meclizine HCl+ Paracetamol + Caffeine 69 Nicergoline + Vinpocetine 70 Gamma Linolenic Acid + Methylcobalamin 71 Beclomethasone Dipropionate + Neomycin Sulphate + Clotrimazole + Lignocaine HCl 72 Boric acid+ Phenylephrine HCl + Naphazoline Nitrate + Menthol + Camphor 73 Naphazoline HCl + Chlorpheniramine Maleate + Zinc Sulphate + Hydroxy Propyl Methyl Cellulose 74 Chlorpheniramine Maleate + Naphazoline HCl + Zinc Sulphate + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 75 Chlorpheniramine Maleate + Naphazoline HCl + Hydroxy Propyl Methyl Cellulose 76 Chlorpheniramine Maleate + Sodium Chloride + Boric Acid + Tetrahydrozoline HCl 77 Chlorpheniramine Maleate + Phenylephrine HCl + Antipyrine 78 Ketorolac Tromethamine + Chlorpheniramine Maleate + Phenylephrine HCl + Hydroxy Propyl Methyl Cellulose 79 Ketorolac Tromethamine + Flurometholone 80 Naphazoline HCl + Zinc Sulphate + Boric Acid + Sodium Chloride+ Chlorpheniramine Maleate 81 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Boric Acid + Borax + Menthol + Camphor 82 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Chlorpheniramine Maleate SN Fixed Dose Combination (FDC) 83 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Menthol + Camphor 84 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 85 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Methylparaben 86 Methenamine + Sodium Benzoate + Benzyl Alcohol 87 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 88 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate + Caffeine 89 Propoxyphene + Chlorpheniramine Maleate 90 Propoxyphene + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 91 Propoxyphene + Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride 92 Sodium Benzoate + Sodium Citrate + Citric Acid 93 Vitamin A Palmitate + Vitamin C + Vitamin E + Vitamin B6 + Vitamin B12 94 Vitamin A Palmitate + Vitamin C + Vitamin E + Niacinamide 95 Vitamin B6 + Vitamin B12 + Vitamin C 96 Vitamin B6 + Vitamin B12 + Niacinamide 97 Vitamin B12 + Vitamin B6 + Vitamin C + Folic Acid 98 Vitamin B12 + Vitamin B6 + Niacinamide + Folic Acid 99 Vitamin C + Vitamin E + Vitamin A + Niacinamide 100 Vitamin D + Calcium + Magnesium 101 Vitamin D + Calcium + Magnesium + Zinc 102 Calcium + Vitamin D + Vitamin K 103 Calcium + Vitamin D + Magnesium + Zinc 104 Calcium + Vitamin D + Vitamin K + Magnesium 105 Calcium + Vitamin D + Vitamin K + Magnesium + Zinc 106 Vitamin E + Vitamin A + Vitamin C + Niacinamide 107 Vitamin E + Vitamin A + Vitamin C + Folic Acid 108 Vitamin E + Vitamin A + Vitamin C + Biotin 109 Vitamin E + Vitamin A + Vitamin C + Vitamin B12 110 Vitamin E + Vitamin C + Folic Acid 111 Vitamin E + Vitamin C + Biotin 112 Vitamin E + Vitamin C + Vitamin B12 113 Vitamin E + Vitamin C + Zinc 114 Calcium + Vitamin D + Omega-3 Fatty Acids 115 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K 116 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Magnesium 117 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Zinc 118 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene 119 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene + Zinc 120 Vitamin C + Vitamin E + Beta-Carotene 121 Vitamin C + Vitamin E + Beta-Carotene + Zinc 122 Vitamin C + Vitamin E + Selenium 123 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids 124 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Magnesium 125 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Zinc 126 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Biotin 127 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 128 Vitamin E + Vitamin A + Vitamin C + Zinc 129 Vitamin E + Vitamin A + Vitamin C + Selenium 130 Vitamin E + Vitamin A + Vitamin C + Biotin 131 Vitamin E + Vitamin A + Vitamin C + Folic Acid + Niacinamide 132 Vitamin E + Vitamin C + Beta-Carotene + Zinc 133 Vitamin C + Vitamin E + Biotin + Folic Acid 134 Vitamin C + Vitamin E + Beta-Carotene + Folic Acid 135 Vitamin C + Vitamin E + Beta-Carotene + Selenium 136 Vitamin E + Vitamin C + Beta-Carotene + Biotin 137 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Biotin 138 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 139 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B12 140 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B6 141 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Folate 142 Calcium + Vitamin D + Magnesium + Vitamin K + Omega-3 Fatty Acids 143 Calcium + Vitamin D + Magnesium + Vitamin K + Biotin 144 Calcium + Vitamin D + Magnesium + Vitamin K + Selenium 145 Calcium + Vitamin D + Magnesium + Vitamin K + Vitamin B12 146 Calcium + Vitamin D + Magnesium + Vitamin K + Folate 147 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B6 148 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B12 149 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Folic Acid 150 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Biotin 151 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Selenium 152 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids 153 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Zinc 154 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Biotin 155 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Selenium 156 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Vitamin B12

Drug Approval

27 Jun 2023

·m.economictimes.com

CORONA remedies buys Sanofi India's ortho brand Myoril

Ahmedabad-based pharmaceutical company CORONA Remedies has acquired the muscle relaxant brand Myoril from Sanofi India for Rs234 crore. The acquisition includes Myoril and its extensions. This acquisition comes after Corona's previous acquisitions of drug brands from GlaxoSmithKline and Abbott India. Myoril, with annual sales of Rs38 crore and a growth rate of 6.8%, will strengthen Corona's presence in the growing muscle relaxant market in India, which is valued at Rs1,626 crore. Ahmedabad-based pharmaceutical company CORONA Remedies has acquired leading muscle relaxant brand Myoril from Sanofi India, for Rs234 crore. Corona has acquired Myoril (Thiocolchicoside) and its extensions such as Myoril Plus (Ketoprofen + Thiocolchicoside), said people aware of the development. Another domestic pharmaceutical majors Torrent Pharma and Eris Lifesciences were also in the race to acquire these orthopaedic brands, said sources. When contacted, a Sanofi spokesperson confirmed the development. The acquisition of the Myoril brand for the Indian market is effective from June 28, 2023, added the spokesperson. Corona Remedies is backed by domestic PE fund ChrysCapital which owns about 30% stake with an investment of about Rs670 crore ($90 million). In 2017, Corona had acquired four drug brands of GlaxoSmithKline - Dilo-BM, Dilo-DX, Stelbid and Vitneurin. Two brands from Abbott India - Obimet and Thyrocab range of products (for diabetes and hyperthyroidism) were also acquired in 2018. The muscle relaxant market in India is valued at Rs. 1,626 crore and it is growing at 13%. Myoril has annual sales of Rs. 38 crore and a growth of 6.8%, according to IQVIA May 2023 data. Sanofi India has been divesting its non-core products as part of concentrating on its core areas such as chronic diseases. As part of the transformation, Sanofi India changed its organisation structure from eight Business Units (BUs) to a focused group of three BUs - Diabetes; Consumer Healthcare; and Transplants & Cardiology, said the company's annual report. Earlier, Sanofi India had sold its nutraceutical portfolio consisting of 16 brands and 30 stock-keeping units (SKUs) to a consortium of Universal Medicare-Kedaara Capital for Rs587 crore in 2021. In the same year, Sanofi India had sold its skin care brands - Soframycin and Sofradex brands to Encube Ehticals for a total consideration of Rs 125 crore. In May, Sanofi India demerged its consumer healthcare business to a wholly owned subsidiary Sanofi Consumer Healthcare India as a value-driven move to accelerate growth for both the pharmaceuticals business and consumer healthcare business in India. There are interest from Indian pharma companies for a few of Sanofi's consumer brands such as DePURA and Combiflam, added sources. The Indian pharmaceutical industry has been growing at an average of 10% over the past five years. In 2022, the industry grew by 6.5%, adding nearly Rs12,000 crore of incremental sales. The demand for acute therapies increased, while most chronic therapies like diabetes and cardiovascular treatments remained relatively steady, said the Sanofi India report. The IQVIA Prognosis Report (2022) projects that the Indian pharmaceuticals market is expected to grow at a CAGR 9.2% between 2021-26 and reach a market size of Rs2,95,100 crore by 2026. The rapid expansion of the e-pharmacy sector, expansion of co-marketing agreements, coupled with the introduction of new OTC regulations will also be a growth driver till 2026.

AcquisitionDrug Approval

100 Deals associated with Thiocolchicoside

External Link

KEGG	Wiki	ATC	Drug Bank
D07276	Thiocolchicoside	M03BX05	DB11582

R&D Status

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Indication	Country/Location	Organization	Date
Muscle Spasticity	-	-	-

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