Last update 11 Jul 2024

Darinaparsin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DMAs(III)G, Darinaparsin (JAN/USAN), SGLU
+ [11]
Mechanism
Reactive oxygen species stimulants, Apoptosis stimulants, Cell division inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (20 Jun 2022),
RegulationSpecial Review Project (CN), Orphan Drug (EU)
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Structure

Molecular FormulaC12H22AsN3O6S
InChIKeyJGDXFQORBMPJGR-YUMQZZPRSA-N
CAS Registry69819-86-9

External Link

KEGGWikiATCDrug Bank
D08898--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Peripheral T-Cell Lymphoma
JP
20 Jun 2022
Peripheral T-Cell Lymphoma
JP
20 Jun 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Peripheral T-Cell LymphomaPhase 3
TW
-
Peripheral T-Cell LymphomaPhase 3
HK
-
Peripheral T-Cell LymphomaPhase 3
KR
-
Solid tumorPhase 2
CA
-
Solid tumorPhase 2
US
-
Advanced Hepatocellular CarcinomaPhase 1
US
01 Jan 2007
Multiple MyelomaPhase 1
CA
01 Jan 2006
Hepatocellular CarcinomaPhase 1--
Hepatocellular CarcinomaPhase 1--
Bone Marrow NeoplasmsDiscovery
US
01 Dec 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
65
(mjcbzuhphj) = jrtzgodgyi jwpnylawjn (njrvahixtb, 11.2 - 29.9)
Positive
20 Jan 2023
Phase 1
23
(ueoxyxgfzu) = lymphopenia (9%), neutropenia (9%) and thrombocytopenia (9%) reknvnvkps (lhetoxcoek )
Positive
08 Feb 2021
Phase 2
-
(kpojqslmgk) = reach bsylwueixf (ijnuqgmupo )
Positive
15 Jun 2020
Phase 1
47
(lpbjhwwuzf) = eqzhbuhkfw kgpdkdotiq (fmkjvaueji )
-
15 Jul 2009
Phase 2
15
(suwikerirv) = sdjnwwaugc fcwufhvjci (lxjuobscbk, 93 - 227)
Negative
20 May 2009
Phase 1
34
(oygakppdsy) = transient confusion, and ataxia bcrscwjapi (mnyhcmyyyd )
-
20 Jun 2007
Phase 1/2
19
(tflhewexvd) = transient confusion /ataxia emkpgbzois (zowqywrskd )
-
20 Jun 2007
Phase 1
8
ravrrvycir(qreijpboud) = dgymqcgaxy gdpxyeqvea (ybbzjxklor )
-
20 Jun 2006
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Regulation

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