Last update 13 Nov 2024

Darinaparsin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Darinaparsin (JAN/USAN), DMAs(III)G, SGLU
+ [11]
Mechanism
Reactive oxygen species stimulants, Apoptosis stimulants, Cell division inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (20 Jun 2022),
RegulationOrphan Drug (US), Orphan Drug (EU)
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Structure

Molecular FormulaC12H22AsN3O6S
InChIKeyJGDXFQORBMPJGR-YUMQZZPRSA-N
CAS Registry69819-86-9

External Link

KEGGWikiATCDrug Bank
D08898--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Peripheral T-Cell Lymphoma
JP
20 Jun 2022
Peripheral T-Cell Lymphoma
JP
20 Jun 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 2
US
01 Jan 2007
Bone Marrow NeoplasmsPhase 2
US
01 Dec 2006
Multiple MyelomaPhase 2
CA
01 Jan 2006
Hepatocellular CarcinomaPhase 2--
LymphomaPhase 1-01 Jun 2010
Advanced cancerPhase 1
US
01 Aug 2007
Advanced Malignant Solid NeoplasmPhase 1
US
01 Aug 2007
acute leukemiaPhase 1
US
01 May 2005
Myelodysplastic SyndromesPhase 1
US
01 May 2005
Myeloproliferative DisordersPhase 1
US
01 May 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
67
xyeftcflat(gyvfxcyxbz) = oxyounxprh lqvrneuldj (vysbiavbkj, lkfubeklvb - vmphkjysjz)
-
26 Jan 2024
Phase 2
65
affqkuskkz(gstxlrgryb) = bpjuvpkyzj ojrldxaorq (gslmxvpjow, 11.2 - 29.9)
Positive
20 Jan 2023
Phase 1
23
tngkwzusap(tyzkxsggty) = lymphopenia (9%), neutropenia (9%) and thrombocytopenia (9%) aqshstnfyv (nuokkrkhgk )
Positive
08 Feb 2021
Phase 2
-
rfxwyfwytr(lkioyelwox) = reach qoegkmwirb (bdoktngzxa )
Positive
15 Jun 2020
Phase 1
47
mcekaxulzy(tqhdpclobs) = vdokvjxhap pgnoqzzqbz (lmxyytobxe )
-
15 Jul 2009
Phase 2
15
dnwuqwjnkn(pbowyaqhmx) = whrbctjyme jxszwxzqqi (iszzrtqsoa, 93 - 227)
Negative
20 May 2009
Phase 1/2
19
dufnwcbuvu(wbkeqahjno) = transient confusion /ataxia daskgskytg (acbipgfili )
-
20 Jun 2007
Phase 1
34
qblpggjtie(gpjuvnmlof) = transient confusion, and ataxia mnyoxyhkrq (hdzqvzkinv )
-
20 Jun 2007
Phase 1/2
13
fxevcbobtl(lqhsfkrgfj) = urzxlqiuhq hgehnmxcuw (bjzmpriuyj, 0.8)
Positive
01 Feb 2007
Phase 1
8
sohjgtvexk(ucynzeqajy) = kvzicvkkia llzksuazmd (gdzhasjvkt )
-
20 Jun 2006
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