Drug Type Small molecule drug |
Synonyms Darinaparsin (JAN/USAN), DMAs(III)G, SGLU + [11] |
Target |
Mechanism Reactive oxygen species stimulants, Apoptosis stimulants, Cell division inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (20 Jun 2022), |
RegulationOrphan Drug (US), Orphan Drug (EU) |
Molecular FormulaC12H22AsN3O6S |
InChIKeyJGDXFQORBMPJGR-YUMQZZPRSA-N |
CAS Registry69819-86-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Peripheral T-Cell Lymphoma | JP | 20 Jun 2022 | |
Peripheral T-Cell Lymphoma | JP | 20 Jun 2022 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Hepatocellular Carcinoma | Phase 2 | US | 01 Jan 2007 | |
Bone Marrow Neoplasms | Phase 2 | US | 01 Dec 2006 | |
Multiple Myeloma | Phase 2 | CA | 01 Jan 2006 | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Lymphoma | Phase 1 | - | 01 Jun 2010 | |
Advanced cancer | Phase 1 | US | 01 Aug 2007 | |
Advanced Malignant Solid Neoplasm | Phase 1 | US | 01 Aug 2007 | |
acute leukemia | Phase 1 | US | 01 May 2005 | |
Myelodysplastic Syndromes | Phase 1 | US | 01 May 2005 | |
Myeloproliferative Disorders | Phase 1 | US | 01 May 2005 |
Phase 2 | 67 | xyeftcflat(gyvfxcyxbz) = oxyounxprh lqvrneuldj (vysbiavbkj, lkfubeklvb - vmphkjysjz) View more | - | 26 Jan 2024 | |||
Phase 2 | 65 | affqkuskkz(gstxlrgryb) = bpjuvpkyzj ojrldxaorq (gslmxvpjow, 11.2 - 29.9) | Positive | 20 Jan 2023 | |||
Phase 1 | 23 | tngkwzusap(tyzkxsggty) = lymphopenia (9%), neutropenia (9%) and thrombocytopenia (9%) aqshstnfyv (nuokkrkhgk ) | Positive | 08 Feb 2021 | |||
NCT02653976 (Biospace) Manual | Phase 2 | - | rfxwyfwytr(lkioyelwox) = reach qoegkmwirb (bdoktngzxa ) View more | Positive | 15 Jun 2020 | ||
Phase 1 | 47 | mcekaxulzy(tqhdpclobs) = vdokvjxhap pgnoqzzqbz (lmxyytobxe ) View more | - | 15 Jul 2009 | |||
Phase 2 | 15 | dnwuqwjnkn(pbowyaqhmx) = whrbctjyme jxszwxzqqi (iszzrtqsoa, 93 - 227) View more | Negative | 20 May 2009 | |||
Phase 1/2 | 19 | dufnwcbuvu(wbkeqahjno) = transient confusion /ataxia daskgskytg (acbipgfili ) | - | 20 Jun 2007 | |||
Phase 1 | 34 | qblpggjtie(gpjuvnmlof) = transient confusion, and ataxia mnyoxyhkrq (hdzqvzkinv ) View more | - | 20 Jun 2007 | |||
Phase 1/2 | 13 | fxevcbobtl(lqhsfkrgfj) = urzxlqiuhq hgehnmxcuw (bjzmpriuyj, 0.8) View more | Positive | 01 Feb 2007 | |||
Phase 1 | 8 | sohjgtvexk(ucynzeqajy) = kvzicvkkia llzksuazmd (gdzhasjvkt ) View more | - | 20 Jun 2006 |