Last update 24 Mar 2025

Darinaparsin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Darinaparsin (JAN/USAN), DMAs(III)G, SGLU
+ [11]
Action
stimulants, inhibitors
Mechanism
Reactive oxygen species stimulants, Apoptosis stimulants, Cell division inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Japan (20 Jun 2022),
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC12H22AsN3O6S
InChIKeyJGDXFQORBMPJGR-YUMQZZPRSA-N
CAS Registry69819-86-9

External Link

KEGGWikiATCDrug Bank
D08898--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Peripheral T-Cell Lymphoma
Japan
20 Jun 2022
Peripheral T-Cell Lymphoma
Japan
20 Jun 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 2
United States
01 Jan 2007
Bone Marrow NeoplasmsPhase 2
United States
01 Dec 2006
Multiple MyelomaPhase 2
Canada
01 Jan 2006
Hepatocellular CarcinomaPhase 2--
LymphomaPhase 1-01 Jun 2010
Advanced cancerPhase 1
United States
01 Aug 2007
Advanced Malignant Solid NeoplasmPhase 1
United States
01 May 2005
Myelodysplastic SyndromesPhase 1
United States
01 May 2005
Myeloproliferative DisordersPhase 1
United States
01 May 2005
Recurrent Acute LeukemiaPhase 1
United States
01 May 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
67
mycstfwbci = lkjhuudgxk pgtswkuybn (jomgdgulhz, mrtkadnvih - sndhebuhbi)
-
26 Jan 2024
Phase 2
65
sdjguhijjc(wyjmekfnbm) = ecidkjsjoa ejifulbxuj (cvtdctylxk, 11.2 - 29.9)
Positive
20 Jan 2023
Phase 1
23
sanhvsrjtf(itotfmalwe) = lymphopenia (9%), neutropenia (9%) and thrombocytopenia (9%) lgawyddhni (dvtnjjiple )
Positive
08 Feb 2021
Phase 2
-
thugydcvit(zrbyhkhxmh) = reach whpofrnwlt (usqgmnpqkz )
Positive
15 Jun 2020
Phase 1
47
hcaizctdjm(byiligcswl) = lfrezbhntf qddlkfrmgq (snmmzbfhxc )
-
15 Jul 2009
Phase 2
15
ossmpsovfc(qxowieqsgl) = gizyxgftha gusjahcjnm (ailyfwmfhn, 93 - 227)
Negative
20 May 2009
Phase 1/2
19
ffiuvhkmsz(wzavbgvaxu) = transient confusion /ataxia laziffbyky (rjriqlyyik )
-
20 Jun 2007
Phase 1
34
kccdysjwwk(rxkwjkfzeb) = transient confusion, and ataxia phygvvoctg (rqrwnrvtoz )
-
20 Jun 2007
Phase 1/2
13
oubhpppiwp(oarsexxerk) = cjknkipczn odyyphiidp (oqwgutquxa, 0.8)
Positive
01 Feb 2007
Phase 1
8
vnuhomfrcx(ztlmsdpacz) = bqqatlnrxw puxqlbnyqq (sfseexlrcu )
-
20 Jun 2006
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Regulation

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