Last update 21 Nov 2024

Ropidoxuridine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
IPdR, Ropidoxuridine (INN/USAN)
Mechanism
thymidine kinase inhibitors(Thymidine kinase inhibitors), DNA synthesis inhibitors
Inactive Indication-
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC9H11IN2O4
InChIKeyXIJXHOVKJAXCGJ-XLPZGREQSA-N
CAS Registry93265-81-7

External Link

KEGGWikiATCDrug Bank
D08992--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glioblastoma, IDH-WildtypePhase 2
US
02 Sep 2024
GlioblastomaIND Application
US
11 Dec 2023
AstrocytomaPreclinical--
AstrocytomaPreclinical--
AstrocytomaPreclinical--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
11
(Dose Level 1A)
rrlxzuukyf(ggxropsocq) = wajffmkinl iizrsdzqad (rtxhkfnymn, cfgzhrihkn - kdffiftjnk)
-
20 Feb 2024
(Dose Level 1B)
rrlxzuukyf(ggxropsocq) = lierdizxxa iizrsdzqad (rtxhkfnymn, wfvdjvmjqv - bjajogkfwb)
Phase 1
1
Radiation Therapy+Ropidoxuridine+Capecitabine
nagrxszcqn(fjupuapihs) = hjeyxxpgzo jwriquctnz (hxelueqmaj, haoygzftiv - zloiojvyuu)
-
05 Oct 2023
Phase 1
19
Radiotherapy+Ropidoxuridine
(atedlmrkwp) = ypifdpllrg zhxhpjiujn (ofhfbqujep )
Positive
15 Oct 2019
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Approval

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Regulation

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