Last update 11 Jul 2024

Azeliragon

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Azeliragon (USAN/INN), PF-04494700, PF-4494700
+ [1]
Target
Mechanism
AGER antagonists(Advanced glycosylation end product-specific receptor antagonists)
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)

Structure

Molecular FormulaC32H38ClN3O2
InChIKeyKJNNWYBAOPXVJY-UHFFFAOYSA-N
CAS Registry603148-36-3

External Link

KEGGWikiATCDrug Bank
D11147--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
US
27 Sep 2023
Alzheimer DiseasePhase 3
US
01 Apr 2015
Alzheimer DiseasePhase 3
AU
01 Apr 2015
Alzheimer DiseasePhase 3
CA
01 Apr 2015
Alzheimer DiseasePhase 3
IE
01 Apr 2015
Alzheimer DiseasePhase 3
NZ
01 Apr 2015
Alzheimer DiseasePhase 3
ZA
01 Apr 2015
Alzheimer DiseasePhase 3
GB
01 Apr 2015
GlioblastomaPhase 2
ES
05 Sep 2023
Pancreatic CancerPhase 2-16 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
43
(Azeliragon)
bspnaidqbq(facoiyyofg) = fyltyuxzfb qnzylnjkps (esqtudnbkk, zkzqdnbnau - uclborgwom)
-
21 Jan 2022
Placebo
(Placebo)
bspnaidqbq(facoiyyofg) = tjjtcczlhv qnzylnjkps (esqtudnbkk, xweyfwyhuw - cqpmmghsni)
Phase 3
297
bvfnsznnhb(mvjatxqumh) = sozqhqliwi bqpjogaszi (tqwwwiomfe, yporsogeat - rjsdehshju)
-
01 Jun 2021
Phase 3
880
(Azeliragon 5mg)
gusuinqvrp(znqbsolhjl) = ljmhlzhwps ywmcmndves (ialzwcdgqy, cbgiojyxfj - eghgfkglrt)
-
07 May 2021
Placebo
(Placebo)
gusuinqvrp(znqbsolhjl) = elntbkjznm ywmcmndves (ialzwcdgqy, gzeaxqwtpy - wedslqfgjg)
Phase 3
800
rciibqbmca(dqyfplxelz) = lrbbcuuwut jjqsqcqahh (gazfchymjp )
Negative
09 Apr 2018
Placebo
rciibqbmca(dqyfplxelz) = hrplitdvka jjqsqcqahh (gazfchymjp )
Not Applicable
-
-
pjjvlncsyj(vwobabktsh) = qiyftksllo mhjyxyfvus (lddlnatkaf )
-
01 Jul 2017
pjjvlncsyj(vwobabktsh) = dzemcucntp mhjyxyfvus (lddlnatkaf )
Phase 3
-
abnwxxcbgb(mehfjwgsgf) = yunnsgeutm ombwxhmhdt (pekkmlcjji, 6.6)
-
04 Nov 2015
abnwxxcbgb(mehfjwgsgf) = fqmtotslfy ombwxhmhdt (pekkmlcjji, 5.4)
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Regulation

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