Last update 13 Dec 2025

KC-706

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KC 706, KC706
Target
p38 MAPK
Action
inhibitors
Mechanism
p38 MAPK inhibitors(P38 mitogen-activated protein kinase inhibitors)
Therapeutic Areas
Immune System DiseasesEndocrinology and Metabolic DiseaseSkin and Musculoskeletal Diseases+ [1]
Active Indication-
Inactive Indication
HyperlipidemiasPemphigusPsoriasis+ [1]
Originator Organization
KemiaKemia
Active Organization-
Inactive Organization
KemiaKemiaKémia, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with KC-706
NCT00606749
/ CompletedPhase 2
A Phase 2 Open-Label Uncontrolled Pilot Study of KC706 in Patients With Stable, Active Pemphigus Vulgaris
EUCTR2006-002645-37-HU
/ CompletedPhase 2
A Phase II randomized double-blind placebo-controlled Study of KC706 in patients with rheumatoid arthritis inadequately controlled with a stable dose of methotrexate
100 Clinical Results associated with KC-706
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100 Translational Medicine associated with KC-706
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100 Patents (Medical) associated with KC-706
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100 Deals associated with KC-706
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External Link

KEGGWikiATCDrug Bank
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DB05157

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PemphigusPhase 2
United States
Kémia, Inc.
01 Nov 2007
HyperlipidemiasPhase 2
Europe
--
Rheumatoid ArthritisPhase 2
Europe
--
PsoriasisPreclinical
United States
--
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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