Last update 29 Jun 2024

Amtolmetin Guacil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amtolmetin, Amtolmetin guacil (INN), Amtolmetin-guacyl
+ [7]
Target
COX
Mechanism
COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
InflammationPain
Inactive Indication-
Originator Organization
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
Active Organization
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
IT (01 Jul 1995),
Inflammation
Regulation-
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Structure

Molecular FormulaC24H24N2O5
InChIKeyCWJNMKKMGIAGDK-UHFFFAOYSA-N
CAS Registry87344-06-7

Related

1
Clinical Trials associated with Amtolmetin Guacil
NCT02865161 / CompletedNot Applicable
Open-label, Multicenter, Observational (Non-interventional) Study of Efficacy and Tolerability of Amtolmetin GuAcil in Subjects With Knee osTeoArthrosis With Dyspepsia. (AGATA)
100 Clinical Results associated with Amtolmetin Guacil
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100 Translational Medicine associated with Amtolmetin Guacil
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100 Patents (Medical) associated with Amtolmetin Guacil
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46
Literatures (Medical) associated with Amtolmetin Guacil
01 Dec 2022Annals of translational medicine
Comparison of cardiorenal safety of nonsteroidal anti-inflammatory drugs in the treatment of arthritis: a network meta-analysis
22 Mar 2016Arthritis
Amtolmetin: A Reappraisal of NSAID with Gastroprotection
01 Jan 2016Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
A choice of a nonsteroidal anti-inflammatory drug with regard to gastrointestinal and cardiovascular risks
100 Deals associated with Amtolmetin Guacil
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External Link

KEGGWikiATCDrug Bank
D07453Amtolmetin Guacil
M01AB03M02AA21
DB16088

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Inflammation
IT
Sigma-Tau Industrie Farmaceutiche Riunite SpASigma-Tau Industrie Farmaceutiche Riunite SpA
01 Jul 1995
Pain---
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
EULAR2019
Not Applicable
Osteoarthritis | Rheumatoid Arthritis | Ankylosing Spondylitis
-
mfhqmpdife(wsxuoispqd) = The development or worsening of arterial hypertension, as well as other cardiovascular complications, was not observed nvpjusfcei (acxgpgifry )
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Positive
12 Jun 2019
EULAR2017
Not Applicable
Osteoarthritis, Knee
220
Amtolmetin guacil (AMG)
xbirrtqafe(qmshqbbqry) = There were no serious adverse events (AE). AE were graded as moderate and mild in 8 and 82% of cases, respectively. AE were recorded in 7.7% of the patients. sotlxvkeut (ishgpngkcl )
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-
14 Jun 2017
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Approval

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Regulation

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