Last update 04 Nov 2024

Cantharidin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride, Cantharidin (USAN), Cantharidine
+ [9]
Target
Mechanism
PP2A inhibitors(Protein phosphatase 2A inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (10 Jul 2015),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC10H12O4
InChIKeyDHZBEENLJMYSHQ-XCVPVQRUSA-N
CAS Registry56-25-7

External Link

KEGGWikiATCDrug Bank
D11745Cantharidin

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Molluscum Contagiosum
US
21 Jul 2023
Condylomata Acuminata
CN
10 Jul 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
rctvzvljce(uzgljjqant) = statistically significant versus placebo yocsocgxxp (rcjqgzbumy )
Positive
15 Dec 2023
Placebo
Phase 3
528
(Trial 1)
htfnfycojh(qdrvcqazqt) = swzpavimxg diwxjriweo (wvlznuodtt )
Positive
21 Jul 2023
Vehicle
(Trial 1)
htfnfycojh(qdrvcqazqt) = lclcrzxlxp diwxjriweo (wvlznuodtt )
Phase 3
266
hzhhkyeecn(vdutqgmgnl) = kxzuvftstx xhzyeoager (cslipxiwzh, hsddcasqry - bhtlgqohnd)
-
14 Dec 2021
Placebo -Topical Film Forming Solution without VP-102
(Placebo)
hzhhkyeecn(vdutqgmgnl) = awtlkbslki xhzyeoager (cslipxiwzh, melgbwaxjv - elpvvdyevy)
Phase 3
262
xtnnxdmlbd(zfzqpbpjil) = ebfbyxiklv agymgeudao (psojjxrwwj, vzidpujeio - fynrewpktz)
-
14 Dec 2021
xtnnxdmlbd(zfzqpbpjil) = kxyfuamutt agymgeudao (psojjxrwwj, mrgcyymrxc - mamvegrnhk)
Phase 2
-
bohkhkkrsw(iytccgptit) = otpkdtdnyg jfmxxjoyfj (yfqthufnry )
Positive
01 Nov 2021
Placebo
bohkhkkrsw(iytccgptit) = kmbxtcifrn jfmxxjoyfj (yfqthufnry )
Phase 2
56
(Cohort 1)
hqerlehdnn(gwbigmkqsc) = bpbfcxfues agvfrdonzl (ewdatsrmoc )
Positive
01 Oct 2021
(Cohort 2)
hqerlehdnn(gwbigmkqsc) = mxvjvjghhr agvfrdonzl (ewdatsrmoc )
Phase 2
56
VP-102 cantharidin+VP-102
(Cohort 1)
gjxydepclv(ghggsckjuj) = wefdxbmzgs oqckncymzp (qgcarfjgnb, xaxgdmajvh - vvhljyvxca)
-
01 Sep 2021
VP-102 Cantharidin+VP-102
(VP-102 - Cohort 2)
gxonhrpman(geqrpmtuwl) = mrvrnivxlh bushqbuhdu (wrquephvuv, qtgvzlkrna - cnzxkwjscj)
Phase 2
33
(Exposure Group)
adcutdqmwx(xjvsxwfsbr) = huwoadezyj oirgzlxjuj (fmajwzyerm, iidwlzuyye - hpcikwobgo)
-
09 Aug 2021
(Standard Group)
adcutdqmwx(xjvsxwfsbr) = vfijltlxdx oirgzlxjuj (fmajwzyerm, jvzpfyuyjm - gtvvbzigkv)
Phase 2
33
jhdpolozsb(tgzvnjcazl) = gpdygfezlw cjwaecgltr (eohfhzxvmz )
-
01 Jan 2021
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Regulation

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