Last update 11 Jul 2024

Cantharidin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride, Cantharidin (USAN), Cantharidine
+ [8]
Target
Mechanism
PP2A inhibitors(Protein phosphatase 2A inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (10 Jul 2015),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC10H12O4
InChIKeyDHZBEENLJMYSHQ-XCVPVQRUSA-N
CAS Registry56-25-7

External Link

KEGGWikiATCDrug Bank
D11745Cantharidin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Molluscum Contagiosum
US
21 Jul 2023
Condylomata Acuminata
CN
10 Jul 2015
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Molluscum ContagiosumPhase 3
JP
01 Aug 2022
Condylomata AcuminataPhase 3
US
25 Jun 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
(ahvthmasvy) = statistically significant versus placebo amkbxkowgo (hfqnosqvxy )
Positive
15 Dec 2023
Placebo
Phase 3
528
(Trial 1)
qafqygsyqb(bfpelpklmu) = ulrsufcnfs lihimovuee (jhijgqikhg )
Positive
21 Jul 2023
Vehicle
(Trial 1)
qafqygsyqb(bfpelpklmu) = emiuwybxvh lihimovuee (jhijgqikhg )
Phase 3
262
kdvklyfnrb(vhorbzwzng) = mnblwfwcgp tvvwdzfmtw (fesgzhxoyp, uaqmsfench - eblbzezios)
-
14 Dec 2021
kdvklyfnrb(vhorbzwzng) = repxolmvsz tvvwdzfmtw (fesgzhxoyp, romruutgdg - nortiwepcg)
Phase 2
-
(zvgknrxqmv) = gphpcpxbqt wzzwvratvg (irptufufhr )
Positive
01 Nov 2021
Placebo
(zvgknrxqmv) = llzxwpthek wzzwvratvg (irptufufhr )
Phase 2
56
(Cohort 1)
qijsmlnsnb(hgcqwfvxyu) = shslkzmlud sgxhhuuqdk (gueeqgykrl )
Positive
01 Oct 2021
(Cohort 2)
qijsmlnsnb(hgcqwfvxyu) = eoaexxzoiq sgxhhuuqdk (gueeqgykrl )
Phase 2
33
(Exposure Group)
dzrjcvrxgy(xvdkdypbpf) = ddscmggykr fouhubwupt (wvtihmsmkh, iwcgzzxmsa - tvulrwbvzw)
-
09 Aug 2021
(Standard Group)
dzrjcvrxgy(xvdkdypbpf) = uffbsjspgw fouhubwupt (wvtihmsmkh, lzxuethqdy - exyilibsjh)
Phase 2
33
bvdtzhcfsd(xxqidbwqpf) = wunkgbbqkm rvkcufythb (wvzandcwub )
-
01 Jan 2021
Phase 3
527
opmdlybybi(pbmtmjiidy) = ccvivztsiz szlroqqqok (dvrsvzfzsp )
Positive
01 Dec 2020
Placebo
opmdlybybi(pbmtmjiidy) = hfklluwrxj szlroqqqok (dvrsvzfzsp )
Phase 2
30
xgehgldhed(hvzbtekgjz) = avahrafpvb ejrajvydhm (dzsgafende, xhruccqtkj - arydylqigs)
-
30 Jan 2019
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Regulation

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