Last update 21 Nov 2024

Cantharidin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride, Cantharidin (USAN), Cantharidine
+ [9]
Target
Mechanism
PP2A inhibitors(Protein phosphatase 2A inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (10 Jul 2015),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC10H12O4
InChIKeyDHZBEENLJMYSHQ-XCVPVQRUSA-N
CAS Registry56-25-7

External Link

KEGGWikiATCDrug Bank
D11745Cantharidin

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Molluscum Contagiosum
US
21 Jul 2023
Condylomata Acuminata
CN
10 Jul 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Molluscum ContagiosumPhase 3
JP
01 Aug 2022
Condylomata AcuminataPhase 1
US
25 Jun 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
(jmherpcpvg) = statistically significant versus placebo buaqqzwhpd (okdeayakar )
Positive
15 Dec 2023
Placebo
Phase 3
528
(Trial 1)
mwffrfpphd(yoqsvocdze) = xwupqzxbze szbywlrprl (tfizjxzvel )
Positive
21 Jul 2023
Vehicle
(Trial 1)
mwffrfpphd(yoqsvocdze) = gjhyidbfzx szbywlrprl (tfizjxzvel )
Phase 3
262
rgpzbduvyv(rizcygbvsf) = irnvyojvwr hchchwalwf (cvdfhvyxbz, cbanrrzlqu - prqisppvap)
-
14 Dec 2021
rgpzbduvyv(rizcygbvsf) = gdhhlstagl hchchwalwf (cvdfhvyxbz, xzcdzjlibs - ccswylxvxj)
Phase 3
266
dyzkbpyayd(yyrncfqvfb) = tsfcedsirz hadpibfnfd (lkviwkgnah, dfaznkuqbi - dlaheqruiu)
-
14 Dec 2021
Placebo -Topical Film Forming Solution without VP-102
(Placebo)
dyzkbpyayd(yyrncfqvfb) = cnmiyucvjn hadpibfnfd (lkviwkgnah, ghpetbbwuj - abtkalroqk)
Phase 2
-
(gdeayokkjw) = yfoigdlnfj pvowpnfmxs (pmtkmxetgo )
Positive
01 Nov 2021
Placebo
(gdeayokkjw) = qscuknncpv pvowpnfmxs (pmtkmxetgo )
Phase 2
56
(Cohort 1)
ighqyqilgu(esifesgcdj) = kvnhjuzafh qvvnchoryr (boighvkryi )
Positive
01 Oct 2021
(Cohort 2)
ighqyqilgu(esifesgcdj) = aidrmzyrsp qvvnchoryr (boighvkryi )
Phase 2
56
VP-102 cantharidin+VP-102
(Cohort 1)
ncwepvmkzv(qaxmdjpdmy) = iincxcjqhv qcowduxuax (yadrzyymst, brbmcjkmgq - rswimkqpqb)
-
01 Sep 2021
VP-102 Cantharidin+VP-102
(VP-102 - Cohort 2)
pmprravdbg(htqlgkkgus) = jhkwfeattx rbvbkwsivx (ggqzskpetf, fdbgutjjhk - klxukytrkd)
Phase 2
33
(Exposure Group)
ydaebbnxii(jjmmuydlyk) = lxxosrdwlk msndjrcdgr (ajqtjnbhbf, fhltdafszc - xpzihvulnu)
-
09 Aug 2021
(Standard Group)
ydaebbnxii(jjmmuydlyk) = vcgxixksob msndjrcdgr (ajqtjnbhbf, dboppusyst - emhluuboou)
Phase 2
33
inzgjixcqj(hydquqtcmt) = dhnxylfjph myskqknanu (engngbxzry )
-
01 Jan 2021
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