Drug Type Monoclonal antibody |
Synonyms Anti-SIRPα - Bristol Myers Squibb, BMS-986351, CC 95251 + [1] |
Target |
Action modulators |
Mechanism SIRPα modulators(Signal-regulatory protein alpha modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |


| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Myelodysplastic Syndromes | Phase 1 | United States | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Australia | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Canada | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | France | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Italy | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Norway | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Spain | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | Sweden | 19 Jan 2022 | |
| Myelodysplastic Syndromes | Phase 1 | United Kingdom | 19 Jan 2022 | |
| Relapsing acute myeloid leukemia | Phase 1 | United States | 19 Jan 2022 |
Phase 1 | 56 | (Part A: Treatment 1) | lxudmlgsyl = kvipnrtajv bivcsvaxop (dtxvolkjtw, blhalgumnl - naheketcgz) View more | - | 25 Sep 2025 | ||
(Part A: Treatment 2) | lxudmlgsyl = zggvridzrd bivcsvaxop (dtxvolkjtw, bsjvkzgact - xtrmaskedg) View more | ||||||
NCT03783403 (EHA2022) Manual | Phase 1 | Non-Hodgkin Lymphoma CD20 Positive | 17 | iuokpuizgc(mlsnqskacv) = frpruqfopr nlokqpxcnc (awzcdybmso ) View more | Positive | 12 May 2022 | |
Phase 1 | Non-Hodgkin's lymphoma refractory CD20 Positive | 18 | chciefqlfu(hkgjaujaqa) = NR gwkbctajiz (kjkjifcsfa ) View more | Positive | 05 Nov 2021 |






