Last update 21 Nov 2024

Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)

Overview

Basic Info

Drug Type
CAR-T
Synonyms-
Target
CD19
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators)
Therapeutic Areas
Immune System DiseasesNervous System DiseasesSkin and Musculoskeletal Diseases+ [1]
Active Indication
DermatomyositisScleroderma, SystemicSystemic Lupus Erythematosus
Inactive Indication-
Originator Organization
Friedrich Alexander Universität Erlangen NürnbergFriedrich Alexander Universität Erlangen Nürnberg
Active Organization
Friedrich Alexander Universität Erlangen NürnbergFriedrich Alexander Universität Erlangen Nürnberg
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)
NCT06347718 / RecruitingPhase 1/2
CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease
100 Clinical Results associated with Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)
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100 Translational Medicine associated with Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)
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100 Patents (Medical) associated with Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)
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100 Deals associated with Anti-CD19 CAR T cell therapy(University of Erlangen-Nürnberg Medical School)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
DermatomyositisPhase 2
DE
Friedrich Alexander Universität Erlangen NürnbergFriedrich Alexander Universität Erlangen Nürnberg
17 Jul 2023
Scleroderma, SystemicPhase 2
DE
Friedrich Alexander Universität Erlangen NürnbergFriedrich Alexander Universität Erlangen Nürnberg
17 Jul 2023
Systemic Lupus ErythematosusPhase 2
DE
Friedrich Alexander Universität Erlangen NürnbergFriedrich Alexander Universität Erlangen Nürnberg
17 Jul 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT06347718 (CASTLE, EULAR2024)
ManualManual
Phase 1/2
Rheumatic Diseases
8
(qcpjckqkzk) = No higher grade CRS (grade 3 or 4) was observed (grade 0: N=3; grade 1: N=4; grade 2: N=1). ltfjenbcqa (sffadbjyat )
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Positive
12 Jun 2024
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Approval

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Regulation

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