Delving into the Latest Updates on TQB-3909 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Target

Bcl-2

Mechanism

Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)

Therapeutic Areas

NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [2]

Active Indication

Mantle cell lymphoma recurrentMantle cell lymphoma refractoryMyelofibrosis+ [12]

Inactive Indication-

Originator Organization

Nanjing Shunxin Pharmaceutical Co., Ltd.

Active Organization

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Nanjing Shunxin Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhasePhase 2

First Approval Date-

Regulation-

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Primary objective: To evaluate the effectiveness of TQ05105 tablets combined with TQB3909 tablets in the treatment of intermediate- and high-risk myelofibrosis (MF). Secondary objective: To evaluate the safety and improvement of related symptoms of TQ05105 tablets combined with TQB3909 tablets in the treatment of intermediate- and high-risk MF subjects.

Start Date09 Mar 2024

Sponsor / Collaborator

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

100 Clinical Results associated with TQB-3909

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100 Translational Medicine associated with TQB-3909

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100 Patents (Medical) associated with TQB-3909

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100 Deals associated with TQB-3909

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Primary Myelofibrosis	Phase 2	CN	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	13 May 2024
Acute Myeloid Leukemia	Phase 2	CN	Nanjing Shunxin Pharmaceutical Co., Ltd.	25 Apr 2024
Myelodysplastic Syndromes	Phase 2	CN	Nanjing Shunxin Pharmaceutical Co., Ltd.	25 Apr 2024
Myeloid Tumor	Phase 2	CN	Nanjing Shunxin Pharmaceutical Co., Ltd.	25 Apr 2024
Chronic Lymphocytic Leukemia	Phase 2	CN	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	11 Oct 2023
Small Lymphocytic Lymphoma	Phase 2	CN	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	11 Oct 2023
Mantle cell lymphoma recurrent	Phase 2	CN	Nanjing Shunxin Pharmaceutical Co., Ltd.	20 Sep 2023
Mantle cell lymphoma refractory	Phase 2	CN	Nanjing Shunxin Pharmaceutical Co., Ltd.	20 Sep 2023
Advanced breast cancer	Phase 2	CN	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	02 Mar 2023
HR Positive/HER2 Negative/Node positive breast cancer	Phase 2	CN	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	02 Mar 2023

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Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT04975204 (TQB3909-I-01, ESMO2024) Manual	Phase 1	Acute Myeloid Leukemia \| Non-Hodgkin Lymphoma	69	TQB3909 (CLL/SLL)	(gddpkuscbr) = None tjgmienfqo (vmmzgwqebs ) View more	Positive	13 Sep 2024
				TQB3909 (B-NHL)