YH2201

The primary study objective was to compare the pharmacokinetic and pharmacodynamic characteristics of a single-dose YH2201 dry suspension (specification: each bag contains 20 mg of esomeprazole magnesium (calculated as C₁₇H₁₇N₃O₃S) and 1680 mg of sodium bicarbonate) with a control drug, esomeprazole magnesium sodium bicarbonate capsules (trade name: Haiyue Huwei®, specification: each capsule contains 20 mg of esomeprazole magnesium (calculated as C₁₇H₁₇N₃O₃S) and 1100 mg of sodium bicarbonate) in healthy Chinese volunteers. The secondary study objective was to evaluate the safety of a single-dose YH2201 dry suspension and a control drug, esomeprazole magnesium sodium bicarbonate capsules, in healthy Chinese volunteers.