Last update 13 Dec 2025

E-2082

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
E 2082
Target
AMPA receptor
Action
antagonists
Mechanism
AMPA receptor antagonists(Glutamate receptor ionotropic AMPA antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Epilepsy, Reflex
Originator Organization
Eisai Co., Ltd.Eisai Co., Ltd.
Active Organization-
Inactive Organization
Eisai, Inc.Eisai, Inc.Eisai Co., Ltd.Eisai Co., Ltd.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with E-2082
NCT03686033
/ TerminatedPhase 2
A Multicenter, Double-Blind, Randomized, Crossover, Single-Dose Study With An Open-Label Treatment Period Evaluating Pharmacodynamic Activity of E2082 in Adult Subjects With Photosensitive Epilepsy
NCT03402178
/ TerminatedPhase 1
A Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Ascending Dose Studies to Assess the Safety, Tolerability, and Pharmacokinetics of E2082 in Healthy Male Subjects
100 Clinical Results associated with E-2082
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100 Translational Medicine associated with E-2082
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100 Patents (Medical) associated with E-2082
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100 Deals associated with E-2082
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Epilepsy, ReflexPhase 2
United States
Eisai, Inc.Eisai, Inc.
31 Oct 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03686033 (CTgov)
Phase 2
Epilepsy, Reflex
8
placebo+E2082
(Treatment A: Placebo)
ffyyzlboal(henuhuaaiy) = suadbixjpe bammnhtfjv (nddnnqreau, 4.604)
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-
28 Sep 2020
(Treatment B: E2082 2.5 mg)
ffyyzlboal(henuhuaaiy) = djpmtmqzus bammnhtfjv (nddnnqreau, 4.336)
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Clinical Trial

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Approval

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Regulation

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