Last update 28 Mar 2025

Zelatriazin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NBI 1065846, TAK 041, TAK-041
Action
agonists
Mechanism
AMPA receptor agonists(Glutamate receptor ionotropic AMPA agonists), GPR139 agonists(Probable G-protein coupled receptor 139 agonists)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H15F3N4O3
InChIKeyJZGLECLGVQRPPI-NSHDSACASA-N
CAS Registry1929519-13-0

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive Disorder, MajorPhase 2
United States
30 Nov 2021
Depressive Disorder, MajorPhase 2
Puerto Rico
30 Nov 2021
AnhedoniaPhase 2
United Kingdom
21 Dec 2017
AnhedoniaPhase 2
United Kingdom
21 Dec 2017
SchizophreniaPhase 2
United Kingdom
21 Dec 2017
SchizophreniaPhase 2
United Kingdom
21 Dec 2017
Cognition DisordersPhase 1
United States
-
Cognition DisordersPhase 1
United Kingdom
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
93
Placebo
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-
31 Jul 2024
Phase 1
-
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Positive
12 Mar 2022
Phase 1
-
12
[11C] (+)-4-propyl-(+)-4-propyl-9-hydroxynaphthoxazine (PHNO)+Amphetamine+TAK -041
(TAK-041 20 mg)
jpouumxfkl(dtdyiimcym) = odihglyfan loljtjyinv (wmnyaukpus, 11)
-
23 Dec 2019
[11C] (+)-4-propyl-(+)-4-propyl-9-hydroxynaphthoxazine (PHNO)+Amphetamine+TAK -041
(TAK-041 40 mg)
jpouumxfkl(dtdyiimcym) = ebrjahgzyt loljtjyinv (wmnyaukpus, 8)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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