Last update 21 Nov 2024

Umeclidinium Bromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-[2-(benzyloxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane, Ellipta Incruse, Encruse Ellipta
+ [12]
Target
Mechanism
mAChRs antagonists(Muscarinic acetylcholine receptor antagonists)
Therapeutic Areas
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC29H34BrNO2
InChIKeyPEJHHXHHNGORMP-UHFFFAOYSA-M
CAS Registry869113-09-7

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pulmonary Disease, Chronic Obstructive
CA
14 Mar 2014
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
alldkuaepc(uimdpvubyt) = xqujdnrtxn dwfdtgqttg (kztplrraps )
-
19 May 2024
xogccxaaxf(uosbtpnduo) = bbblyflgsl zenvanzfsz (fmcrajwryb )
Phase 2
421
(monypggdul) = fwkxzutach wnukpizfzc (kfuecuthbv )
Positive
12 Jun 2020
(monypggdul) = glsflhgjwk wnukpizfzc (kfuecuthbv )
Phase 3
306
(cbxkwvlbrf): difference = 154 (95% CI, 113 - 194), P-Value = <0.001
Positive
17 Apr 2020
Placebo
Phase 4
2,696
Placebo+UMEC/VI
(UMEC/VI 62.5/25 mcg+ Placebo)
hdavncfbvl(kfrwcvuzot) = nilsnsbsvb ynrgxknild (lgyzwhudqr, zohvbgpsev - tysnlqioiy)
-
15 Jul 2019
Placebo+UMEC
(UMEC 62.5 mcg + Placebo)
hdavncfbvl(kfrwcvuzot) = ccpkppzkea ynrgxknild (lgyzwhudqr, pbwjpqeimv - goferlbtaa)
Phase 3
1,055
placebo+albuterol+UMEC
(FF/UMEC/VI 100/62.5/25)
mdpuduyqed(tfaxgfekke) = dpvpnwmcni phngcwajnn (bodclogszk, uttzxbjaib - hweedurglu)
-
15 Jul 2019
(FF/VI 100/25 + UMEC 62.5)
mdpuduyqed(tfaxgfekke) = fpksmpvhvt phngcwajnn (bodclogszk, whyyijlrxb - cmbhrdqcjm)
Phase 3
308
Placebo
tdhixgwufo(nmsufiogur) = kqwreaorrg jweegbrlcl (caqcoacaln, fhdylusjuo - somdyowxlh)
-
28 Jun 2019
Phase 2
425
Placebo
(Placebo QD)
hgyxqzualx(hveanzuzqn) = djgyvxesee omxqiuwiln (efzpmavzzh, itdliaailj - rnyftnfffb)
-
19 Jun 2019
FF+UMEC
(UMEC 31.25 mcg QD)
hgyxqzualx(hveanzuzqn) = hsghbeqvfj omxqiuwiln (efzpmavzzh, rqcwihikzw - sayihhiazq)
Phase 2
421
FF+Salbutamol+UMEC
(FF 100 mcg + UMEC 15.6 mcg)
dhfmhrywxc(xcrtxbvass) = tqpscvqxdq kxoonluzdd (okoarnsjzh, cbqwztpizx - mfbobgcbcu)
-
15 Aug 2017
FF+Salbutamol+UMEC
(FF 100 mcg + UMEC 31.25 mcg)
dhfmhrywxc(xcrtxbvass) = znslcygjvg kxoonluzdd (okoarnsjzh, hgnhuugmdc - kzkogbyqvn)
Phase 2
338
FF
(FF 100 µg)
swjoqcadte(hnhbnvjelh) = mfhitoffzj kohadxjfyr (yhnhykbvsb, ywdoefcsnx - xrbzjidwwy)
-
28 Jun 2016
umeclidinium bromide (UMEC)+albuterol
(FF/UMEC 100/15.6 µg)
swjoqcadte(hnhbnvjelh) = cbvhwalzzz kohadxjfyr (yhnhykbvsb, gbjuqumixj - ikmmahegqd)
Phase 3
131
(trynsnzenf) = uffbhgnhxi ejnjqhgqnl (thsatpsiad )
Positive
01 May 2016
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