Clinical Trials associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

NCT03621670

/ CompletedPhase 3

Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy Infants

The purpose of this study is to evaluate the safety and immunogenicity of Bexsero (meningococcal group B vaccine-rMenB+OMV NZ) in North American infants 6 weeks through 12 weeks of age, when administered concomitantly with Pneumococcal conjugate vaccine (PCV 13) and other recommended routine infant vaccines(RIV).

Start Date27 Jul 2018

Sponsor / Collaborator

GSK Plc

NCT03207750

/ CompletedPhase 3

Immunogenicity, Reactogenicity and Safety Study of Pediarix®, Hiberix® and Prevenar 13® Co-administered With Two Different Formulations of GSK Biologicals' HRV Vaccine (444563) in Healthy Infants 6-12 Weeks of Age

The purpose of this study is to assess if there is any immune interference between the Porcine circovirus free (PCV-free) liquid Human rotavirus (HRV) vaccine and routine infant vaccinations currently in use in the US, namely Pediarix®, Hiberix® and Prevenar 13® as compared to the currently licensed lyophilized formulation of the HRV vaccine when co-administered with the same routine vaccinations in healthy infants 6-12 weeks of age

Start Date14 Sep 2017

Sponsor / Collaborator

GSK Plc

NCT02447978

/ CompletedNot Applicable

Duration of Protection Following Five Doses of GlaxoSmithKline's (GSK's) DTaP Vaccines in School Age Children

The purpose of this study is to assess duration of protection for GSK DTaP vaccines in preventing pertussis.

Start Date01 Feb 2015

Sponsor / Collaborator

GSK Plc

100 Clinical Results associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

100 Translational Medicine associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

100 Patents (Medical) associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

Literatures (Medical) associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

02 May 2023·Vaccine

Newborn medication adherence and childhood under-immunization in military beneficiaries.

Article

Author: Drumm, Caitlin M ; Vereen, Rasheda J ; Aden, James K

BACKGROUND:

The American Academy of Pediatrics recommends birth doses of vitamin K, erythromycin ointment, and the hepatitis B vaccine, but the relationship between birth medication administration and childhood immunization compliance is understudied. The objective of this study is to evaluate rates of newborn medication administration, and risk factors for refusal in military beneficiaries and determine the relationship between medication refusal and under-immunization at 15 months.

METHODS:

A retrospective chart review was completed for all term and late preterm infants born at Brooke Army Medical Center, San Antonio, TX, from January 1, 2016, to December 31, 2019. The electronic medical record was queried for birth medication administration, maternal age, active-duty status, rank, and birth order. Childhood immunization records were extracted for all patients who continued care at our facility. A patient was considered completely immunized if they had received at least 22 vaccines by 15 months: three doses of the hepatitis B vaccine [Pediarix^TM], two doses of the rotavirus vaccine [Rotarix^TM], four doses of the DTAP vaccine [Pediarix^TM and Acel-Immune^TM], three doses of Haemophilus influenza B vaccine [Pedvaxhib^TM], four doses of pneumococcal [Prevnar 13^TM], three doses of IPV [Pediarix^TM], one dose of measles, mumps, and rubella [MMR^TM], one dose of varicella [Varivax^TM] and one dose of hepatitis A vaccine [Harvix^TM].

RESULTS:

Seven thousand one hundred and forty infants were included; 99.3% received vitamin K, 98.8% received erythromycin ointment, and 93.8% received the hepatitis B vaccine. Refusal of the erythromycin ointment and hepatitis B vaccine was associated with older maternal age and higher birth order. Childhood immunization records were available for 607 infants; 7.2% (n = 44) were under-immunized by 15 months, with no infants being non-immunized. Refusal of the hepatitis B vaccine (RR: 2.9 (CI 1.16-7.31)) only at birth was associated with a higher risk of being under-immunized.

CONCLUSIONS:

Refusal of the hepatitis B vaccine in the nursery is associated with a risk of being under-immunized in childhood. Obstetric and pediatric providers should be aware of this association for appropriate family counseling.

30 Sep 2021·Statistics in medicineQ3 · MEDICINE

Exact sequential test for clinical trials and post‐market drug and vaccine safety surveillance with Poisson and binary data

Q3 · MEDICINE

Article

Author: Kulldorff, Martin ; R. Silva, Ivair ; Maro, Judith

Abstract:

In sequential analysis, hypothesis testing is performed repeatedly in a prospective manner as data accrue over time to quickly arrive at an accurate conclusion or decision. In this tutorial paper, detailed explanations are given for both designing and operating sequential testing. We describe the calculation of exact thresholds for stopping or signaling, statistical power, expected time to signal, and expected sample sizes for sequential analysis with Poisson and binary type data. The calculations are run using the packageSequential, constructed inRlanguage. Real data examples are inspired on clinical trials practice, such as the current efforts to develop treatments to face the COVID‐19 pandemic, and the comparison of treatments of osteoporosis. In addition, we mimic the monitoring of adverse events following influenza vaccination and Pediarix vaccination.

02 Aug 2020·Expert review of vaccinesQ2 · MEDICINE

Safety profile of Infanrix hexa – 17 years of GSK’s passive post-marketing surveillance

Q2 · MEDICINE

Article

Author: Hanssens, Linda ; Verheust, Céline ; Dolhain, Jan ; Puente Gómez, Ivonne

INTRODUCTION:

This paper reports 17 years of passive safety surveillance of routine use of the pediatric hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b-conjugate vaccine (DTPa-HBV-IPV/Hib, Infanrix hexa, GSK).

METHODS:

Global post-licensure passive surveillance data collected in GSK's central safety database since DTPa-HBV-IPV/Hib's launch (2000) are described.

RESULTS:

The most common spontaneously reported adverse events (AEs) after DTPa-HBV-IPV/Hib vaccination in children were fever (reporting rate: 7.74/100,000 doses distributed), crying (2.62/100,000), injection site erythema (1.87/100,000) and swelling (1.28/100,000). A review of extensive limb swelling did not reveal any safety concerns. An observed-to-expected analysis did not show an increased risk of sudden death after DTPa-HBV-IPV/Hib vaccination, in line with previous observations. The analyses confirmed that increases in spontaneous reporting proportions of convulsions with/without fever and hypotonic-hyporesponsive episodes after co-administration of DTPa-HBV-IPV/Hib and 13-valent pneumococcal conjugate vaccine remained small and their clinical significance unknown. The most common vaccination errors were mistakes in the vaccination schedule. Reporting of preparation errors (mostly reconstitution) was low and did not impact the vaccine's benefit-risk profile.

CONCLUSIONS:

Seventeen years of post-licensure experience confirm confidence in the safety profile of DTPa-HBV-IPV/Hib in routine use, with a favorable benefit-risk profile in infants and toddlers.

PLAIN LANGUAGE SUMMARY:

What is the context? The cornerstone of childhood vaccination in many countries worldwide is a vaccine that protects against several diseases: diphtheria, tetanus, whooping cough, hepatitis B, polio and Haemophilus influenzae type b infections (such as meningitis). One of these vaccines (the longest on the market) is called Infanrix hexa; it has been available for infants and toddlers since 2000. After a vaccine is included in a country's routine vaccination program, its safety is constantly checked; this is done in clinical trials and through spontaneous reporting of adverse events after vaccination. It is important to share up-to-date information on the safety of vaccines, particularly since concerns about vaccine safety in parents may lead to lower vaccination rates an disease outbreaks. Here we summarize 17 years of safety data for the Infanrix hexa vaccine. What is new? We analyzed spontaneously reported adverse events after Infanrix hexa vaccinations between 2000 and 2017 The most commonly reported adverse events were fever, crying and injection site redness and swelling An in-depth review of extensive limb swelling after Infanrix hexa vaccination revealed no safety concerns. There was no increased risk of sudden death after Infanrix hexa vaccination, consistent with what was shown in several other studies. As shown previously, seizures were more common when Infanrix hexa was given together with the pneumococcal conjugate vaccine, Prevnar 13, than when it was given alone. What is the take-home message? The large amount of safety data gathered from clinical trials and from spontaneous adverse event reporting during 17 years of routine vaccination with Infanrix hexa supports its continued use in young children.

News (Medical) associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

28 Jun 2022

·www.prnewswire.com

United States Human Vaccines Markets, 2018-2021 & Forecast to 2028: Approval/launches of the New Vaccines / Rising Focus on Immunization Programs / Increasing Investments and Government Support

DUBLIN, June 28, 2022 /PRNewswire/ -- The "United States Human Vaccines Market Size, Share, Top 45 Human Vaccines Brand In-depth Analysis, Emerging Trends, Current Analysis, Growth, Demand, Opportunity, and Forecast 2022 - 2028" report has been added to ResearchAndMarkets.com's offering. Amid the COVID-19 crisis, the United States human vaccines market is poised to grow by US$ 31,517 million by 2028, accelerating at a CAGR of 7% during the forecast period. The prominent factors that are expected to contribute to the growth of the United States human vaccines market: Increased Disease Awareness Approval/launches of the New Vaccines Rising Focus on Immunization Programs Increasing Investments and Government Support for the Vaccines Development The report contains a deep analysis of the United States human vaccines market size in terms of value. The report provides a clear insight into current and future developments of the United States vaccines market. The report also explores the detailed analysis, insights of the top 45 vaccines market assessment in the United States from 2018 to 2021, and forecasts to 2028. The report also details the latest information about the vaccine's pricing analysis, insights, and trends, and the regulatory framework of the United States human vaccines market. After conducting thorough research on the historical and current growth parameters, the growth prospects of the United States human vaccines market are obtained with maximum precision. This new 2022 market report provides a holistic analysis of the entire United States human vaccines market. The report offers the most up-to-date industry data on the actual market situation and future outlook for the United States' human vaccines market. The report also tracks and analyses competitive developments, including collaboration, partnership deals, distribution, exclusive and licensing agreements, new vaccine developments, and R&D activities in the market. The report also delivers an in-depth analysis of evolving market trends, drivers, and restraining forces that influence the growth of the market. The report also analyses detailed profiles of innovative and leading players with information on business overview, companies' vaccines portfolio, promising vaccines in the clinical development, and the newest developments The report will serve as a source for a 360-degree analysis, thoroughly integrating different models. This Newest and Comprehensive the United States Human Vaccines Market Research Report 2022 Delivers: Comprehensive Research Methodology of the United States Human Vaccines Market Detailed and Extensive Market Overview with Key Analyst Insights Insights about Market Determinants that are Stimulating the United States Human Vaccines Market To Analyze the Historical Growth in the Market Size of the United States Human Vaccines Market from 2018 to 2021 To Estimate and Forecast the Market Size of the United States Human Vaccines Market from 2022 to 2028 and Growth Rate until 2028 Detailed Insights of the Top 45 Human Vaccines Market Value Used in the U.S. with Six Years Forecast An Insightful Analysis of the Top 45 Vaccines Brand Market Share and Y-o-Y Growth Rate Delivers All-inclusive Insights on the Latest Pricing Analysis, Insights, and Trends Delivers an In-Depth Analysis of Evolving Market Trends, Drivers, and Restraints of the United States Human Vaccines Market An Insightful Investigation has been done on Promising Human Vaccines in the Clinical Development Delivers Comprehensive Insights into the Regulatory Framework of the United States Human Vaccines Market Tracks Competitive Developments, Approaches, Recent Industry Developments, Partnership, Collaboration Deals, Distribution, Exclusive, and Licensing Agreement A Comprehensive List of the Leading Companies along with the Analysis of their Current Vaccines Portfolio, Promising Human Vaccines in the Clinical Development, and Present Development The Report Helps Answer the Following Questions: What is the current scenario of the United States human vaccines market? What is the total market size and forecast (until 2028) of the United States human vaccines market? How big is the United States human vaccines market? At what CAGR is the U.S. human vaccines market projected to grow in the forecast period (2022-2028)? What are the leading human vaccines? What are their revenue potentials to 2028? Which human vaccine brand provides the highest market share? What is the regulatory framework in the United States vaccines market? What are the key factors driving the United States human vaccines market? What are the key challenges of the United States human vaccines market? What are the major deals and agreement happenings in the United States human vaccines market? What are the United States human vaccines pricing trends and analysis? What are the various human vaccines available in the United States? Who are the topmost market players? What are their happenings, current developments, and scenarios? How is the market predicted to develop in the future? Key Topics Covered: 1. Executive Summary 2. United States Human Vaccines Market Size and Forecast (2018 - 2028) 3. United States Human Vaccines Brand Market Share and Y-o-Y Growth (%), 2018 - 2028 4. Key Market Growth Drivers and Challenges in the United States Human Vaccines Market 4.1 Key Market Growth Drivers 4.2 Key Market Challenges 5. United States Top 45 Human Vaccines Market Value Analysis, Insights and Forecasts, 2018 - 2028 5.1 Daptacel 5.2 Quadracel 5.3 Kinrix 5.4 Vaxelis 5.5 IPOL 5.6 Vaqta 5.7 Havrix 5.8 Twinrix 5.9 Engerix B 5.10 PedvaxHIB 5.11 ActHIB 5.12 Hiberix 5.13 MenQuadfi 5.14 Tenivac 5.15 Imovax 5.16 FluMist Quadrivalent 5.17 Prevnar 13 5.18 Gardasil 9 5.19 Fluzone Quadrivalent 5.20 Flublok 5.21 Flucelvax Quadrivalent 5.22 Afluria Quadrivalent 5.23 Fluad 5.24 Varivax 5.25 Menactra 5.26 Proquad 5.27 Pneumovax 23 5.28 Fluarix 5.29 FluLaval 5.30 M-M-R II 5.31 Adacel 5.32 Boostrix 5.33 Bexsero 5.34 Menveo 5.35 Trumenba 5.36 Shingrix 5.37 Pentacel 5.38 Recombivax HB 5.39 Rotateq 5.40 Rotarix 5.41 Pediarix 5.42 Infanrix 5.43 Heplisav-B 5.44 TDVAX 5.45 BioThrax 5.46 Other Vaccines 6. United States Human Vaccines Pricing Analysis, Insights and Trends 7. Regulatory Framework of the United States Human Vaccines Market 8. Major Deals and Agreement Happenings in the Human Vaccines Market 8.1 Merger & Acquisitions 8.2 Collaboration Deals 8.3 Licensing Agreement 8.4 Exclusive Agreement 8.5 Distribution Agreement 8.6 Partnership Deals 9. Leading Companies in the United States Human Vaccines Market 9.1 Sanofi Pasteur 9.1.1 Business Overview 9.1.2 Human Vaccines Portfolio 9.1.3 Promising Human Vaccines in the Clinical Development 9.1.4 Recent Development 9.3 Merck 9.4 Pfizer 9.5 Seqirus (CSL Limited) 9.6 AstraZeneca 9.7 Dynavax Technologies Corporation 9.8 Emergent BioSolutions Inc. For more information about this report visit Media Contact: Research and Markets Laura Wood, Senior Manager [email protected] For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 U.S. Fax: 646-607-1904 Fax (outside U.S.): +353-1-481-1716 Logo: SOURCE Research and Markets

VaccineAcquisition

02 Jun 2021

·www.biospace.com

First Six-In-One Pediatric Combination Vaccine Now Available in the United States

With a new combination vaccination available in the United States, taking your child to the doctor to get vaccines might become a little less of a hassle. Or at the very least, less frequent. On Tuesday, it was announced that a new pediatric combination vaccine is now available in the U.S. The new vaccination, dubbed VAXELIS, is indicated for active immunization to help prevent diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and invasive disease due to Haemophilus influenzae type b. It is the first and only six-in-one pediatric combination vaccine available in the United States. The vaccine was developed by Merck and Sanofi Pasteur and is approved to be used as a 3-dose series in children six weeks through four years of age. “Given the potential to reduce the number of shots by as many as three in the first six months of life, as compared to pentavalent vaccines plus hepatitis B or Haemophilus influenzae type b vaccines, VAXELIS represents an important option for healthcare professionals and parents,” said Joanne Monahan, senior vice president, U.S. Vaccines, Merck. “Merck and Sanofi have been in contact with the major insurers and the appropriate pricing publications to notify them of the availability of VAXELIS, and we look forward to working with payers and providers to deliver this novel hexavalent vaccine to age-appropriate children.” While VAXELIS is the first six-in-one vaccine in the United States, combination vaccines in general have been around for a while (since the mid-1940s). In fact, some of them are so common, some people might not even realize they fall under this category. A combination vaccine is when two or more vaccines that could be given individually are put together into one shot. Some common combination shots include MMR (measles, mumps and rubella) and DTaP (diphtheria, tetanus and pertussis), although they could not be considered true combo vaccines because they aren't available as separate vaccines in the United States. Other common pediatric combination vaccines include Pediarix, ProQuad, Kinrix and Pentacel. Some of the benefits of combination vaccines include fewer shots, on-time protection, fewer visits to the doctor and less hassle overall. The U.S.-based partnership between Merck and Sanofi Pasteur under which VAXELIS was developed was established in 1991, and utilizes the companies' development, manufacturing and marketing experience for individual and combination vaccines.

Vaccine

02 Jun 2021

·www.biospace.com

First Six-In-One Pediatric Combination Vaccine VAXELIS Now Available in the United States

The new vaccination, dubbed VAXELIS, is indicated for active immunization to help prevent diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and invasive disease due to Haemophilus influenzae type b. VAXELIS is open for sale in US. With a new combination vaccination available in the United States, taking your child to the doctor to get vaccines might become a little less of a hassle. Or at the very least, less frequent. On Tuesday, it was announced that a new pediatric combination vaccine is now available in the U.S. The new vaccination, dubbed VAXELIS, is indicated for active immunization to help prevent diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and invasive disease due to Haemophilus influenzae type b. It is the first and only six-in-one pediatric combination vaccine available in the United States. The vaccine was developed by Merck and Sanofi Pasteur and is approved to be used as a 3-dose series in children six weeks through four years of age. “Given the potential to reduce the number of shots by as many as three in the first six months of life, as compared to pentavalent vaccines plus hepatitis B or Haemophilus influenzae type b vaccines, VAXELIS represents an important option for healthcare professionals and parents,” said Joanne Monahan, senior vice president, U.S. Vaccines, Merck. “Merck and Sanofi have been in contact with the major insurers and the appropriate pricing publications to notify them of the availability of VAXELIS, and we look forward to working with payers and providers to deliver this novel hexavalent vaccine to age-appropriate children.” While VAXELIS is the first six-in-one vaccine in the United States, combination vaccines in general have been around for a while (since the mid-1940s). In fact, some of them are so common, some people might not even realize they fall under this category. A combination vaccine is when two or more vaccines that could be given individually are put together into one shot. Some common combination shots include MMR (measles, mumps and rubella) and DTaP (diphtheria, tetanus and pertussis), although they could not be considered true combo vaccines because they aren’t available as separate vaccines in the United States. Other common pediatric combination vaccines include Pediarix, ProQuad, Kinrix and Pentacel. Some of the benefits of combination vaccines include fewer shots, on-time protection, fewer visits to the doctor and less hassle overall. The U.S.-based partnership between Merck and Sanofi Pasteur under which VAXELIS was developed was established in 1991, and utilizes the companies’ development, manufacturing and marketing experience for individual and combination vaccines.

VaccineDrug Approval

100 Deals associated with Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

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KEGG	Wiki	ATC	Drug Bank
-	-	J07CA12	-

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Approved

10 top approved records.

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Indication	Country/Location	Organization	Date
Diphtheria	European Union	GlaxoSmithKline Biologicals SA	23 Oct 2000
Diphtheria	Iceland	GlaxoSmithKline Biologicals SA	23 Oct 2000
Diphtheria	Liechtenstein	GlaxoSmithKline Biologicals SA	23 Oct 2000
Diphtheria	Norway	GlaxoSmithKline Biologicals SA	23 Oct 2000
Hepatitis B	European Union	GlaxoSmithKline Biologicals SA	23 Oct 2000
Hepatitis B	Iceland	GlaxoSmithKline Biologicals SA	23 Oct 2000
Hepatitis B	Liechtenstein	GlaxoSmithKline Biologicals SA	23 Oct 2000
Hepatitis B	Norway	GlaxoSmithKline Biologicals SA	23 Oct 2000
Poliomyelitis	European Union	GlaxoSmithKline Biologicals SA	23 Oct 2000
Poliomyelitis	Iceland	GlaxoSmithKline Biologicals SA	23 Oct 2000
Poliomyelitis	Liechtenstein	GlaxoSmithKline Biologicals SA	23 Oct 2000
Poliomyelitis	Norway	GlaxoSmithKline Biologicals SA	23 Oct 2000
Tetanus	European Union	GlaxoSmithKline Biologicals SA	23 Oct 2000
Tetanus	Iceland	GlaxoSmithKline Biologicals SA	23 Oct 2000
Tetanus	Liechtenstein	GlaxoSmithKline Biologicals SA	23 Oct 2000
Tetanus	Norway	GlaxoSmithKline Biologicals SA	23 Oct 2000
Whooping Cough	European Union	GlaxoSmithKline Biologicals SA	23 Oct 2000
Whooping Cough	Iceland	GlaxoSmithKline Biologicals SA	23 Oct 2000
Whooping Cough	Liechtenstein	GlaxoSmithKline Biologicals SA	23 Oct 2000
Whooping Cough	Norway	GlaxoSmithKline Biologicals SA	23 Oct 2000

Developing

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Rotavirus Infections	Phase 3	United States	GSK Plc	14 Sep 2017
Viral gastroenteritis due to Rotavirus	Phase 3	United States	GSK Plc	14 Sep 2017
Haemophilus Infections	Phase 3	Finland	GSK Plc	01 Apr 2006
Haemophilus Infections	Phase 3	Italy	GSK Plc	01 Apr 2006
Meningitis	Phase 3	Finland	GSK Plc	01 Apr 2006
Meningitis	Phase 3	Italy	GSK Plc	01 Apr 2006

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT03207750 (CTgov)	Phase 3	Rotavirus Infections \| Viral gastroenteritis due to Rotavirus	1,280	Hiberix+human rotavirus (HRV) vaccine+PCV+Prevnar-13+Pediarix (HRV Porcine Circovirus (PCV)-Free Liquid Group)	feiaheohdv = hlqwyetjwm dwidzijqul (rbtijfmwys, czkcqzmcab - jokmpehkcf) View more	-	31 Oct 2019
				Hiberix+human rotavirus (HRV) vaccine+Prevnar-13+Pediarix (HRV Lyophilized Group)	feiaheohdv = ulmtgdfczi dwidzijqul (rbtijfmwys, anabybelbx - rumrggtlhf) View more
NCT00129116 (CTgov)	Phase 2	Meningitis \| Haemophilus Infections	388	Hib-MenCY-TT vaccine+Infanrix penta ® (Menhibrix F1/Infanrix-penta Group)	kvbfksqhii = wauqlpqwrw wyzigkgxyc (emidaxowzh, bzdovoyfhn - qjobaqdtnn) View more	-	23 Jul 2012
				Hib-MenCY-TT vaccine+Infanrix penta ® (Menhibrix F2/Infanrix-penta Group)	kvbfksqhii = xadnazwdcr wyzigkgxyc (emidaxowzh, vjjoadbcjr - yfsbdmdebi) View more
NCT00586612 (CTgov)	Phase 3	Meningitis \| Haemophilus Infections	313	Menitorix™+Infanrix™ IPV+Prevenar™+Infanrix™ penta (Preterm Group)	snhzqbufxq = qcbqwxzltn fyvhvacowz (awxoffovcr, gkjayqituf - hiukngmmre) View more	-	22 Jan 2010
				Menitorix™+Infanrix™ IPV+Prevenar™+Infanrix™ penta (Full-term Group)	snhzqbufxq = iehhyydccq fyvhvacowz (awxoffovcr, tivyjqwibj - qjbosvullm) View more

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Diphtheria, tetanus, pertussis (acellular, component), hepatitis-B (rDNA) and poliomyelitis (inactivated) vaccine (GlaxoSmithKline Plc)

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