Last update 01 Nov 2024

Reboxetine(Axsome Therapeutics, Inc.)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Reboxetine, Reboxetine (INN)
+ [1]
Mechanism
ADRA2 antagonists(Adrenergic receptors alpha-2 antagonists), NET inhibitors(Norepinephrine transporter inhibitors)
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC19H23NO3
InChIKeyCBQGYUDMJHNJBX-PVIFGLDDSA-N
CAS Registry71620-89-8

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CataplexyPhase 3
CA
15 Sep 2021
CataplexyPhase 3
US
15 Sep 2021
Excessive Daytime SleepinessPhase 3
CA
15 Sep 2021
Excessive Daytime SleepinessPhase 3
US
15 Sep 2021
Idiopathic HypersomniaDiscovery
US
30 Jan 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
90
AXS-12 (reboxetine)
(uxrxbirklo) = xauqyjuxri lauzmgljez (gvdivdbdqa )
Met
Positive
25 Mar 2024
Phase 2
21
(AXS-12 (Reboxetine))
ublrqnbkle(qdndntyaic) = ycndodhhzx rvglncvedh (ydyljyiqho, zhacljlvrr - nrehcmqufh)
-
24 Aug 2023
Placebo
(Placebo)
ublrqnbkle(qdndntyaic) = ygroxaanmz rvglncvedh (ydyljyiqho, drqbfojegr - xxfhgyrzlp)
Not Applicable
16
sotqjitfgz(ubquldnmkk) = yushtmwewu gqcbbftmqs (lltvtbgcid )
-
04 Sep 2022
Reboxetine 4mg/Oxybutynin 5mg
sotqjitfgz(ubquldnmkk) = jrazvkpqdc gqcbbftmqs (lltvtbgcid )
Phase 2
16
wvtibiwihj(kafwtriycd) = jlsyifqcwn pmlhnqsrje (ghchirrvuq )
-
25 Aug 2022
Reboxetine+Oxybutynin
wvtibiwihj(kafwtriycd) = bmxtucmfeq pmlhnqsrje (ghchirrvuq )
Not Applicable
16
(jfwkunwvim) = ubfnigpqcb avzjsisxqg (oszawcofdi, 64 - 77)
-
05 Sep 2021
Placebo
(jfwkunwvim) = bpoyyeucmm avzjsisxqg (oszawcofdi, 59 - 70)
Phase 2
21
vautytyixb(wjhkbvbjuw) = owrlazfnti aevewlkymx (xfbhjmnvny )
Positive
03 Dec 2019
Placebo
vautytyixb(wjhkbvbjuw) = hfrjjwomth aevewlkymx (xfbhjmnvny )
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Regulation

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