Request Demo
Last update 03 Aug 2026
EX-103
Last update 03 Aug 2026
Overview
Basic Info
Drug Type Bispecific T-cell Engager (BiTE) |
Synonyms Anti-CD3/anti-CD20 bispecific T-cell engager, EX 103, EX103 |
Target |
Action inhibitors, stimulants |
Mechanism CD20 inhibitors(B-lymphocyte antigen CD20 inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Login to view timeline
Related
1
Clinical Trials associated with EX-103NCT06021678
A Phase I/II Study Evaluating the Safety, Efficacy, and Pharmacokinetics of EX103 in Subjects with Relapsed/Refractory CD20-Positive Non-Hodgkin Lymphoma
100 Clinical Results associated with EX-103
Login to view more data
100 Translational Medicine associated with EX-103
Login to view more data
100 Patents (Medical) associated with EX-103
Login to view more data
100 Deals associated with EX-103
Login to view more data
R&D Status
10 top R&D records. to view more data
Login
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| CD20 positive Non-Hodgkin Lymphoma | Phase 2 | China | 25 Oct 2021 | |
| Chronic Lymphocytic Leukemia | Phase 1 | United States | 30 Jan 2022 | |
| Chronic Lymphocytic Leukemia | Phase 1 | China | 30 Jan 2022 | |
| Non-Hodgkin Lymphoma | Phase 1 | United States | 30 Jan 2022 | |
| Systemic Lupus Erythematosus | IND Approval | China | 30 Jul 2026 | |
| B-cell lymphoma recurrent | IND Application | China | 05 Jun 2026 |
Login to view more data
Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | - | kcxesnhgqz(nhastdnoaw) = CRS events were the most common treatment related adverse events and occurred in 66.7% of the patients, with 50.7% grade 1, 14.5% grade 2, one patient (1.4%) experienced grade 3, and no higher events occurred. tazsfhkxsu (bfnfsbzwsb ) View more | - | 08 Dec 2024 | |||
Phase 1/2 | 23 | fdojobvpsr(kudvoduqii) = All CRS events were grade (Gr) 1-2 (Gr 1: 78.3%, Gr 2: 13.0%), no Gr 3 or higher events viivxaviev (naotaqvkvy ) View more | Positive | 24 May 2024 | |||
Phase 1 | 13 | exajbrzpdc(kjkpwivldw) = The most common adverse events were CRS and pyrexia, all were grade (Gr) 1-2, no Gr 3 or higher. Most CRS occurred in 1st or 2nd cycle, and resolved within 48 hours. No neurologic AE occurred. nguqbeoqxq (wuyitpmgsz ) | Positive | 23 Oct 2023 | |||
(DLBCL patients) |
Login to view more data
Translational Medicine
Boost your research with our translational medicine data.
login
or
Deal
Boost your decision using our deal data.
login
or
Core Patent
Boost your research with our Core Patent data.
login
or
Clinical Trial
Identify the latest clinical trials across global registries.
login
or
Approval
Accelerate your research with the latest regulatory approval information.
login
or
Biosimilar
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
login
or
Regulation
Understand key drug designations in just a few clicks with Synapse.
login
or
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free