Last update 01 Nov 2024

TG-1801

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators), CD47 inhibitors(Cluster of differentiation 47 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Lymphocytic LeukemiaPhase 2
US
28 Apr 2021
Follicular LymphomaPhase 2
US
28 Apr 2021
Mantle-Cell LymphomaPhase 2
US
28 Apr 2021
Marginal Zone B-Cell LymphomaPhase 2
US
28 Apr 2021
Mediastinal large B-cell lymphomaPhase 2
US
28 Apr 2021
Small Lymphocytic LymphomaPhase 2
US
28 Apr 2021
B-Cell Malignant NeoplasmPhase 1
CH
30 Jan 2022
B-Cell Malignant NeoplasmPhase 1
CH
30 Jan 2022
B-Cell LymphomaPhase 1
AU
05 Mar 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
B-Cell Lymphoma
CD19+ | CD47
30
(tpdxaganoj) = lzknsmwpxe mgliawhegw (jwmkheilcw )
Positive
09 Jun 2023
TG-1801 + ublituximab combination therapy
(mnhyolbsup) = imuhitkguy ervvzxwfbb (btammkrydp )
Phase 1
30
(kkkmclrplp) = 1 infusion reaction [500 mg monotherapy], 1 rash [360 mg monotherapy] hvxdeashtf (ojfkgtfiox )
Positive
11 Dec 2022
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Core Patent

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Clinical Trial

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Approval

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Regulation

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