Last update 21 Nov 2024

2X-121

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Stenoparib
+ [2]
Mechanism
PARP1 inhibitors(Poly (ADP-Ribose) polymerase 1 inhibitors), PARP2 inhibitors(Poly (ADP-Ribose) Polymerase 2 inhibitors), TNKS1 inhibitors(tankyrase inhibitors)
+ [1]
Originator Organization
Active Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC18H15N5O
InChIKeyJLFSBHQQXIAQEC-UHFFFAOYSA-N
CAS Registry1140964-99-3

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic breast cancerPhase 2
DK
20 Jun 2018
SarcomaDiscovery
US
21 Oct 2018
Kidney NeoplasmsDiscovery
US
21 Sep 2018
NeuroblastomaDiscovery
US
10 Sep 2018
Advanced Malignant Solid NeoplasmDiscovery
GB
01 Jan 2012
Chronic Lymphocytic LeukemiaDiscovery
GB
01 Jan 2012
MelanomaDiscovery
GB
01 Jan 2012
Ovarian CancerDiscovery
GB
01 Jan 2012
Triple Negative Breast CancerDiscovery
GB
01 Jan 2012
B-Cell LymphomaDiscovery
GB
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
41
zhjobulyld(vnmlplrfzd) = fatigue, n = 4, 800 mg; anaphylaxis, n = 1, 600 mg fdwwzykmfo (omihqwyyfo )
-
11 Jun 2020
Phase 1
25
(cabmymmjmp) = zlahphlqtz gqfprepjgz (snveymmscc )
-
20 May 2014
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Clinical Trial

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Approval

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Regulation

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