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Last update 22 Nov 2025
TAK-058
Last update 22 Nov 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms ENV-8058, TAK 058 |
Target |
Action antagonists |
Mechanism 5-HT3 receptor antagonists(5-hydroxytryptamine receptors, ionotropic (HTR3) antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with TAK-058NCT02614586
A Placebo-Controlled Study to Evaluate the Effect of a Single Dose of TAK-058 and Ondansetron on P50 Auditory Gating in Subjects With Stable Schizophrenia
NCT02389881
A Phase 1, Randomized, Placebo-Controlled, Double-Blind, Safety, Tolerability, and Pharmacokinetic Study in Healthy Subjects After Multiple Oral Doses of TAK-058
NCT02153099
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Safety, Tolerability and Pharmacokinetic Study of Escalating Single Doses of ENV8058 in Healthy Subjects
100 Clinical Results associated with TAK-058
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100 Translational Medicine associated with TAK-058
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100 Patents (Medical) associated with TAK-058
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100 Deals associated with TAK-058
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Schizophrenia | Phase 1 | United States | 01 Feb 2015 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 40 | (Cohort 1 Non-elderly Healthy: TAK-058 25 mg) | jegeqjulhg = wpnmnwxsan rybxtunaja (nshmaskehs, esazgdkrow - nmsfdlondu) View more | - | 23 Feb 2017 | ||
(Cohort 2 Non-elderly Healthy: TAK-058 75 mg) | jegeqjulhg = moyrhcvlqr rybxtunaja (nshmaskehs, poutfgdhyz - qavahhoptc) View more | ||||||
Phase 1 | - | 48 | (Cohort 4: TAK-058 5 mg) | dxgxzobfry = corzvlgyem ujxcizyisf (qvxgsxhaie, udgcfezdcg - ppyfttmsta) View more | - | 17 Dec 2015 | |
(Cohort 1: TAK-058 15 mg) | dxgxzobfry = zckjbxvael ujxcizyisf (qvxgsxhaie, wdsnwibbuj - jicvpokjck) View more |
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