Last update 30 Apr 2026

Mometasone furoate/Nortriptyline Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mometasone/nortriptyline, Nortriptyline/mometasone, CRX-191
Target
GR x MAO
Action
agonists, inhibitors
Mechanism
GR agonists(Glucocorticoid receptor agonists), MAO inhibitors(Monoamine oxidase inhibitors)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal DiseasesOther Diseases
Active Indication-
Inactive Indication
AtrophyPsoriasis
Originator Organization
Zalicus, Inc.Zalicus, Inc.
Active Organization-
Inactive Organization
Zalicus, Inc.Zalicus, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H22ClN
InChIKeySHAYBENGXDALFF-UHFFFAOYSA-N
CAS Registry894-71-3
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Related

1
Clinical Trials associated with Mometasone furoate/Nortriptyline Hydrochloride
NCT00544687
/ CompletedPhase 1
A Phase I, Single-Center, Randomized, Vehicle and Active-Controlled Study to Assess and Compare the Atrophy-Causing Potential of Topical CRx-191 Formulations in Healthy Volunteers
100 Clinical Results associated with Mometasone furoate/Nortriptyline Hydrochloride
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100 Translational Medicine associated with Mometasone furoate/Nortriptyline Hydrochloride
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100 Patents (Medical) associated with Mometasone furoate/Nortriptyline Hydrochloride
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100 Deals associated with Mometasone furoate/Nortriptyline Hydrochloride
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PsoriasisPhase 2
Germany
Zalicus, Inc.Zalicus, Inc.
-
AtrophyPhase 1
Germany
Zalicus, Inc.Zalicus, Inc.
01 Sep 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Clinical Trial

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Approval

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Regulation

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