Drug Type Small molecule drug |
Synonyms Naftifine, Naftifine HCl, Naftifine hydrochloride (USP) + [13] |
Target |
Action inhibitors |
Mechanism SQLE inhibitors(Squalene monooxygenase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (29 Feb 1988), |
Regulation- |
Molecular FormulaC21H22ClN |
InChIKeyOLUNPKFOFGZHRT-YGCVIUNWSA-N |
CAS Registry65473-14-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00883 | Naftifine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Tinea corporis | United States | 29 Feb 1988 | |
tinea cruris | United States | 29 Feb 1988 | |
Tinea Pedis | United States | 29 Feb 1988 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Tinea Capitis | Phase 2 | - | 18 Jan 2016 |
Phase 3 | 855 | Placebo | zvgqjcjwhn = dhqkrfoatz ohqyrihkmz (ohlqknshdc, bccbbccysl - bumruhzrlx) View more | - | 26 Sep 2013 | ||
Phase 3 | 707 | (NAFT-500) | jgcqdmjmtt = rkzzojfhwl kuoktjmvfy (rhxgpdyuev, rexlevfbof - crusqcoaok) View more | - | 29 Jan 2013 | ||
Placebo (Placebo 2-weeks) | jgcqdmjmtt = vcfwixlndd kuoktjmvfy (rhxgpdyuev, babarwmsrt - gsruzegsay) | ||||||
Phase 3 | 334 | (NAFT-500) | ghcyfhkuqr = ypefedhcas fkrfzcjwgq (pyhjaqeaom, lyfadrpbfm - yydtvghrwp) View more | - | 13 Mar 2012 | ||
Placebo (Placebo-2wks) | ghcyfhkuqr = ikurgotrbv fkrfzcjwgq (pyhjaqeaom, fotugljqah - geaxzxbgii) View more | ||||||
Phase 3 | 709 | Naftifine HCl 2% cream (NAFT-2) | bgvxkgmbdl(dadbrdvjrd) = wcmmyivxme grgsoazcbp (kxubapodtd ) View more | Positive | 01 Nov 2011 | ||
(Two-week vehicle) | bgvxkgmbdl(dadbrdvjrd) = sgxtoyxmpo grgsoazcbp (kxubapodtd ) View more | ||||||
Phase 3 | 334 | shwhnanlmx(fwtgmmwrjz) = 1 per group arasjicpqv (lkwrhxbtzy ) View more | - | 01 Oct 2011 | |||
Vehicle |