Last update 27 Jan 2026

CJRB-101

Overview

Basic Info

Drug Type
Microbiota
Synonyms
CJRB-101
Target
TLR4
Action
agonists
Mechanism
TLR4 agonists(Toll like receptor 4 agonists)
Therapeutic Areas
NeoplasmsRespiratory DiseasesSkin and Musculoskeletal Diseases
Active Indication
Advanced cancerAdvanced Malignant Solid NeoplasmMelanoma+ [3]
Inactive Indication-
Originator Organization
CJ Bioscience, Inc.CJ Bioscience, Inc.
Active Organization
CJ Bioscience, Inc.CJ Bioscience, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CJRB-101
NCT05877430
/ RecruitingPhase 1/2
Phase 1/2 Open Label, Safety and Preliminary Efficacy Study of a Live Biotherapeutic Product (CJRB-101) in Combination With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
100 Clinical Results associated with CJRB-101
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100 Translational Medicine associated with CJRB-101
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100 Patents (Medical) associated with CJRB-101
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100 Deals associated with CJRB-101
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 2
United States
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Advanced cancerPhase 2
South Korea
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Advanced Malignant Solid NeoplasmPhase 2
United States
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Advanced Malignant Solid NeoplasmPhase 2
South Korea
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
MelanomaPhase 2
United States
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
MelanomaPhase 2
South Korea
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Neoplasm MetastasisPhase 2
United States
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Neoplasm MetastasisPhase 2
South Korea
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Non-Small Cell Lung CancerPhase 2
United States
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
Non-Small Cell Lung CancerPhase 2
South Korea
CJ Bioscience, Inc.CJ Bioscience, Inc.
11 Sep 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT05877430 (First-in-human study of CJRB-101, ASCO2025)
Phase 1/2
Neoplasm Metastasis
32
srgzwegdld(otwtwurblz) = Only 1 patient (3.2%) experienced grade≥3 TRAE which was anemia related to CJRB-101 weejhzeqad (cocpspctkm )
Positive
30 May 2025
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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