Last update 21 Nov 2024

Grapiprant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Grapiprant (USAN/INN)
+ [11]
Target
Mechanism
EP4 antagonists(Prostanoid EP4 receptor antagonists)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC26H29N5O3S
InChIKeyHZVLFTCYCLXTGV-UHFFFAOYSA-N
CAS Registry415903-37-6

External Link

KEGGWikiATCDrug Bank
D10638Grapiprant-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cancer PainPhase 2
CN
22 Dec 2021
Non-Small Cell Lung CancerPhase 2--
Non-Small Cell Lung CancerPhase 2--
OsteoarthritisPreclinical
US
01 Nov 2006
Stomach UlcerPreclinical
US
01 Nov 2006
Inflammatory Breast NeoplasmsDiscovery
US
04 Nov 2021
Metastatic breast cancerDiscovery
US
04 Nov 2021
PainDiscovery
US
18 Oct 2018
HypersensitivityDiscovery
JP
-
InflammationDiscovery
JP
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
54
(nhvqiujobo) = qliybocram tfczdnhhfp (iyzsaojtuo )
Positive
08 Dec 2022
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Clinical Trial

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Approval

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Regulation

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