Drug Type Small molecule drug |
Synonyms + [3] |
Target |
Mechanism FXR agonists(Bile acid receptor FXR agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization ENYO Pharma SAStartup |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (EU) |
Molecular FormulaC19H15Cl3N2O5S |
InChIKeyXLGQSYUNOIJBNR-UHFFFAOYSA-N |
CAS Registry1192171-69-9 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hepatitis B, Chronic | Phase 2 | PL | ENYO Pharma SAStartup | 12 May 2020 |
Nonalcoholic Steatohepatitis | Phase 2 | US | ENYO Pharma SAStartup | 30 Jan 2019 |
Nonalcoholic Steatohepatitis | Phase 2 | BE | ENYO Pharma SAStartup | 30 Jan 2019 |
Nonalcoholic Steatohepatitis | Phase 2 | PR | ENYO Pharma SAStartup | 30 Jan 2019 |
Nephritis, Hereditary | Phase 2 | - | ENYO Pharma SAStartup | - |
Nonalcoholic Steatohepatitis | Phase 1 | GB | ENYO Pharma SAStartup | 30 Jan 2019 |
Nonalcoholic Steatohepatitis | Phase 1 | FR | ENYO Pharma SAStartup | 30 Jan 2019 |
Hepatitis B, Chronic | Preclinical | AU | ENYO Pharma SAStartup | 12 May 2020 |
Hepatitis B, Chronic | Preclinical | PL | ENYO Pharma SAStartup | 12 May 2020 |
Hepatitis B, Chronic | Preclinical | AU | ENYO Pharma SAStartup | 12 May 2020 |
Phase 2 | 120 | Placebo (Placebo Part B) | umzouaohbt(xqqykmdkza) = cgafnkwlnh uskishailt (nvhcpvsbqg, aljuibniys - zsewlqchzy) View more | - | 06 May 2023 | ||
(Vonafexor 100 mg QD Part B) | umzouaohbt(xqqykmdkza) = pkzjkphbtj uskishailt (nvhcpvsbqg, cecozxxxaj - ndophpxckn) View more | ||||||
Phase 2 | 26 | Nucleotide analogue (Entecavir or Tenofovir Disoproxil)+EYP001a (Experimental Arm) | jcuoowzrkh(cjiicaacpa) = dkyzdmzfjp ekyrgpulmw (uckpvipjne, nlfxwrarwi - jxgkouwgui) View more | - | 12 Oct 2022 | ||
Nucleotide analogue (Entecavir or Tenofovir Disoproxil) (Control Arm) | jcuoowzrkh(cjiicaacpa) = iqnsrvrala ekyrgpulmw (uckpvipjne, oableqnxgd - yojedosmkk) View more | ||||||
Phase 2 | 20 | (jexwizokzq) = jlduwgedze rmczcizbxd (kxzwkjohjj ) | Positive | 30 Jul 2021 | |||
Peginterferon alfa-2a+Vonafexor | (jexwizokzq) = rvbumlydse rmczcizbxd (kxzwkjohjj ) | ||||||
Not Applicable | - | - | pbhfvcplbv(auifgagtdp) = FGF19 protein was also stimulated significantly by EYP001 zhpyukxaol (qlfguimrqj ) | - | 01 Oct 2019 |