Last update 26 Dec 2024

Chlorpheniramine Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane, 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine, 2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine
+ [45]
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists)
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (13 Jul 1949),
Regulation-
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Structure

Molecular FormulaC20H23ClN2O4
InChIKeyDBAKFASWICGISY-BTJKTKAUSA-N
CAS Registry113-92-8

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Oedema vascular
JP
31 Aug 2007
Angioedema
JP
20 Jul 1984
Eczema
JP
24 Apr 1984
Skin Diseases
JP
24 Apr 1984
Dermatitis
CN
01 Jan 1981
Dermatitis
CN
01 Jan 1981
Drug Eruptions
CN
01 Jan 1981
Drug Eruptions
CN
01 Jan 1981
Drug Eruptions
CN
01 Jan 1981
Drug Eruptions
CN
01 Jan 1981
Drug Eruptions
CN
01 Jan 1981
Edema
JP
27 Jan 1961
Pruritus
JP
27 Jan 1961
Respiratory Tract Infections
JP
27 Jan 1961
Rhinitis, Allergic
JP
27 Jan 1961
Rhinitis, Allergic, Seasonal
JP
27 Jan 1961
Rhinitis, Vasomotor
JP
27 Jan 1961
Hypersensitivity
US
13 Jul 1949
Urticaria
US
13 Jul 1949
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
HN
27 Jul 2022
Cutaneous hypersensitivityPhase 1
CN
19 Feb 2019
NeurodermatitisPhase 1
CN
19 Feb 2019
Photosensitivity DisordersPhase 1
CN
19 Feb 2019
Pruritis (itchy skin)Phase 1
CN
19 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Chlorpheniramine Maleate (CPM) 10-day treatment
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-
21 May 2023
Not Applicable
-
tvejegxdcc(mreimsphiw) = epslvbylrf smdenmeuom (cpuwbvzvqt )
Positive
10 Jul 2021
Control group
tvejegxdcc(mreimsphiw) = jbyosslrsb smdenmeuom (cpuwbvzvqt )
Phase 2/3
24
qyckkshwor(eninksazjg) = vsxwqpcpqk qfcqgflfut (wvgcjmfptc )
-
01 Apr 2001
qyckkshwor(eninksazjg) = ydhbrwfchs qfcqgflfut (wvgcjmfptc )
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Regulation

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