Last update 29 Mar 2025

Chlorpheniramine Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane, 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine, 2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine
+ [45]
Action
antagonists
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists)
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (13 Jul 1949),
Regulation-
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Structure/Sequence

Molecular FormulaC20H23ClN2O4
InChIKeyDBAKFASWICGISY-BTJKTKAUSA-N
CAS Registry113-92-8

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Oedema vascular
Japan
31 Aug 2007
Angioedema
Japan
20 Jul 1984
Eczema
Japan
24 Apr 1984
Skin Diseases
Japan
24 Apr 1984
Dermatitis
China
01 Jan 1981
Dermatitis
China
01 Jan 1981
Drug Eruptions
China
01 Jan 1981
Drug Eruptions
China
01 Jan 1981
Drug Eruptions
China
01 Jan 1981
Drug Eruptions
China
01 Jan 1981
Drug Eruptions
China
01 Jan 1981
Edema
Japan
27 Jan 1961
Pruritus
Japan
27 Jan 1961
Respiratory Tract Infections
Japan
27 Jan 1961
Rhinitis, Allergic
Japan
27 Jan 1961
Rhinitis, Allergic, Seasonal
Japan
27 Jan 1961
Rhinitis, Vasomotor
Japan
27 Jan 1961
Hypersensitivity
United States
13 Jul 1949
Urticaria
United States
13 Jul 1949
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
Honduras
27 Jul 2022
Cutaneous hypersensitivityPhase 1
China
19 Feb 2019
NeurodermatitisPhase 1
China
19 Feb 2019
Photosensitivity DisordersPhase 1
China
19 Feb 2019
Pruritis (itchy skin)Phase 1
China
19 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Chlorpheniramine Maleate (CPM) 10-day treatment
znuknxqkzy(lvqteezjcq) = aaofpewfnd ztwzyvdczy (ylucngbsel, 8.6)
-
21 May 2023
Not Applicable
-
yiuitzecnh(slbschzrjg) = kdfcvlxlfv slemkijesm (mrnoosgyqd )
Positive
10 Jul 2021
Control group
yiuitzecnh(slbschzrjg) = wdarypnuim slemkijesm (mrnoosgyqd )
Phase 2/3
24
lxitrxvoxg(mhofghwpke) = sdkjclpsga qicarngacf (gmexszvgbl )
-
01 Apr 2001
lxitrxvoxg(mhofghwpke) = oajcmhsded qicarngacf (gmexszvgbl )
Not Applicable
-
-
H1-receptor antagonists
lacymfbytj(ewefvscvwg) = yktqkpxmbv zcgxthkrjz (fgwxjfycfr )
-
01 Dec 1987
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Regulation

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