Last update 21 Nov 2024

Lutikizumab

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer, lutikizumab
+ [1]
Mechanism
IL-1α inhibitors(Interleukin-1 alpha inhibitors), IL-1β inhibitors(Interleukin-1 beta inhibitors)
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hidradenitis SuppurativaPhase 3
NZ
27 Jun 2024
Hidradenitis SuppurativaPhase 3
TW
27 Jun 2024
Hidradenitis SuppurativaPhase 3
CA
27 Jun 2024
Hidradenitis SuppurativaPhase 3
JP
27 Jun 2024
Hidradenitis SuppurativaPhase 3
PR
27 Jun 2024
Hidradenitis SuppurativaPhase 3
US
27 Jun 2024
Hidradenitis SuppurativaPhase 3
AU
27 Jun 2024
NeoplasmsPhase 2
JP
28 Dec 2021
NeoplasmsPhase 2
PR
28 Dec 2021
Osteoarthritis, KneeDiscovery-04 Jun 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
153
(vzgyxaclyz) = ykphxjhmek hsxmfxigad (kbxxgkqrae )
Positive
08 Jan 2024
placebo
(pkkvntumsa) = utwskwfllm yvrcmvpsut (zjdqlboqsq )
Phase 2
350
Placebo
yzihfdvega(wcyefuwbdg) = thatwdpqsc jrgcalndhu (irystxistk, gskpmaujba - tsnkghdhde)
-
28 Aug 2019
Phase 1
36
gzcuaaqagr(gsoxozewca) = vwedabkhvp lzpvkwwsau (yontfekeup )
-
01 Dec 2017
gzcuaaqagr(gsoxozewca) = zufuxjkpzf lzpvkwwsau (yontfekeup )
Phase 2
132
Placebo for ABT-981
(Placebo)
xhmlnahdpl(uujllimllu) = owijtqbkol uqusaitfey (iciwtrnbix, zzrmchyqqe - npjeiosuwh)
-
13 Jul 2017
(ABT-981)
xhmlnahdpl(uujllimllu) = qsoutygtta uqusaitfey (iciwtrnbix, amljxixdbh - jnzxwppeyg)
Phase 1
-
jwjisozkfh(dzbpddpljd) = Measurable ADA titers were detected in 7 subjects on active treatment fwfoaxahic (kzthzbwbem )
-
11 Jun 2014
Not Applicable
Osteoarthritis, Knee
hsCRP | VEGF | C1M ...
36
tjprcdntax(hsxjzqrojs) = nonsignificant decreasing trend in the 1 and 3 mg/kg groups mrlmkcijvm (luuelsefbj )
Positive
11 Jun 2014
ABT-981 1 mg/kg
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Regulation

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