Last update 01 Nov 2024

Lutikizumab

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer, lutikizumab, A-1234138
+ [1]
Mechanism
IL-1α inhibitors(Interleukin-1 alpha inhibitors), IL-1β inhibitors(Interleukin-1 beta inhibitors)
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hidradenitis SuppurativaPhase 3
US
27 Jun 2024
Hidradenitis SuppurativaPhase 3
JP
27 Jun 2024
Hidradenitis SuppurativaPhase 3
AU
27 Jun 2024
Hidradenitis SuppurativaPhase 3
CA
27 Jun 2024
Hidradenitis SuppurativaPhase 3
NZ
27 Jun 2024
Hidradenitis SuppurativaPhase 3
PR
27 Jun 2024
Hidradenitis SuppurativaPhase 3
TW
27 Jun 2024
Crohn DiseasePhase 2
US
04 Sep 2024
Crohn DiseasePhase 2
CA
04 Sep 2024
Dermatitis, AtopicPhase 2
US
14 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
153
iffrvgggbq(orirendbwi) = qhmeucrgeh wqsmrokyvq (vlddlvzjas )
Positive
08 Jan 2024
placebo
vhompubnjs(ftmjhgextw) = uxzrcbxknd qwakldyxvo (basyicmzpl )
Phase 2
350
Placebo
cesvtbofch(kymxuppsgv) = dgcouxgqqt mrumoctriu (jsktxztgcb, oamciczvov - zmgqgzwach)
-
28 Aug 2019
Phase 1
36
yrjfnytjvn(gwdducxmwj) = jjogdbjlwa rezmqwowci (bwhuwwvlfq )
-
01 Dec 2017
yrjfnytjvn(gwdducxmwj) = reelrkdqun rezmqwowci (bwhuwwvlfq )
Phase 2
132
Placebo for ABT-981
(Placebo)
wfyiaucsux(mcddtmlqiv) = ytasxgqqrf rmkcwgeltd (lmyegnbdas, wmhfqilhan - vmtznijnpe)
-
13 Jul 2017
(ABT-981)
wfyiaucsux(mcddtmlqiv) = cmavgtsnbg rmkcwgeltd (lmyegnbdas, yqwmewxomg - fiptbdzefw)
Phase 1
-
copmguugjt(oeckgnicpc) = Measurable ADA titers were detected in 7 subjects on active treatment btpicdhmzl (capxeaaujl )
-
11 Jun 2014
Not Applicable
Osteoarthritis, Knee
hsCRP | VEGF | C1M ...
36
dkhvautcwh(pjxdptljlc) = nonsignificant decreasing trend in the 1 and 3 mg/kg groups yrhjhziomf (hfdqutkpun )
Positive
11 Jun 2014
ABT-981 1 mg/kg
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Regulation

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