Last update 26 Jun 2025

YPT-01

Overview

Basic Info

Drug Type
Bacteriophage therapy
Synonyms-
Target
PcrV
Action
inhibitors
Mechanism
PcrV inhibitors(Pseudomonas aeruginosa PvrV protein inhibitors)
Therapeutic Areas
Infectious DiseasesCongenital DisordersDigestive System Disorders+ [2]
Active Indication-
Inactive Indication
Cystic FibrosisPseudomonas aeruginosa infection
Originator Organization
Yale UniversityYale University
Active Organization-
Inactive Organization
Yale UniversityYale University
License Organization-
Drug Highest PhasePendingPhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with YPT-01
NCT04684641
/ CompletedPhase 1/2IIT
CYstic Fibrosis bacterioPHage Study at Yale (CYPHY): A Single-site, Randomized, Double-blind, Placebo-controlled Study of Bacteriophage Therapy YPT-01 for Pseudomonas Aeruginosa Infections in Adults With Cystic Fibrosis
100 Clinical Results associated with YPT-01
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100 Translational Medicine associated with YPT-01
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100 Patents (Medical) associated with YPT-01
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100 Deals associated with YPT-01
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cystic FibrosisPhase 2
United States
Yale UniversityYale University
29 Mar 2021
Pseudomonas aeruginosa infectionPhase 2
United States
Yale UniversityYale University
29 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT04684641 (CTgov)
Phase 1/2
Pseudomonas aeruginosa infection | Cystic Fibrosis
8
(Phage Therapy)
jkyfhvtblm(sozszqorct) = dtdstljxyd ubzejegxwr (bvpcyspmuy, 1.62)
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-
03 Mar 2023
Placebo
(Placebo)
jkyfhvtblm(sozszqorct) = pwmjzubkuh ubzejegxwr (bvpcyspmuy, 1.77)
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Clinical Trial

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Approval

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Regulation

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