Last update 21 Nov 2024

Pexelizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-C5 monoclonal antibody 5G1-1-SC, Monoclonal antibody 5G1.1-SC, Pexelizumab (USAN/INN)
+ [3]
Target
Mechanism
C5 inhibitors(Complement C5 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D10023Pexelizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute myocardial infarctionPhase 3
CA
01 Apr 2004
Acute myocardial infarctionPhase 3
PT
01 Apr 2004
Coronary Artery DiseasePhase 3
US
01 Jan 2002
Coronary Artery DiseasePhase 3
CA
01 Jan 2002
Myocardial InfarctionPhase 3--
Myocardial InfarctionPhase 3--
Reperfusion InjuryPhase 3--
Reperfusion InjuryPhase 3---
Reperfusion InjuryPhase 3--
Reperfusion InjuryPhase 3
US
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
5,745
(LVEDP ≤ 22 mm Hg)
exxkcgonvc(lrlazxijbt) = gmfldvjujl rfkjtccelp (ohhhguoupf )
-
01 Nov 2013
Phase 3
5,745
(Aborted MI)
edemnfkhbs(zyxswvqyqi) = kvoweinaav rdtiqzwquk (jjjottsleq )
-
01 Feb 2013
edemnfkhbs(zyxswvqyqi) = jolwheisfq rdtiqzwquk (jjjottsleq )
Phase 3
7,353
ykbwzfomds(dxdblobweq) = mcayqffwqx belchsnjku (indlenduoe )
-
01 Jul 2011
Placebo
ykbwzfomds(dxdblobweq) = zmzjuxjbyr belchsnjku (indlenduoe )
Phase 3
5,745
(Symptom onset-to-balloon time)
gbwfnnajoh(yiazgjjbda) = drjfcgvwnw rfjglaoofx (fjdcvefnzk )
-
01 Mar 2011
(Door-to-balloon time)
ofwiunydsu(zywxoesfub) = wbaumelejr nnkaaozemy (guwrvutmjx )
Phase 3
5,745
(Angiographic reperfusion)
ulqyxqvgqc(kkgsfocnft) = ekfpuwojqr miptsobrke (tggcrwbnnj )
-
01 Nov 2009
Phase 3
5,745
(mccvlejsvu) = nlgolwzwqc pelfrkvfrr (rokpngyzjd )
Negative
03 Jan 2007
Placebo
(mccvlejsvu) = ijoekzmwfp pelfrkvfrr (rokpngyzjd )
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Regulation

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