Last update 01 Jul 2024

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-

External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
HIV InfectionsPhase 3
US
01 Aug 2016
Heterozygous familial hypercholesterolemiaPhase 3
US
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
BG
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
CA
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
FI
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
IT
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NL
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NO
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
PL
23 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
wdicadhnaa(ebsizqucar) = umwsrozlpq bilhwmbdkc (ddreycoeuv )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
eqppcqztwg(bhbpfsiezt) = hqorjirjtc dilodgbenz (rveaipjsfr, xiirfyppqq - ekqeepchau)
-
19 Jun 2019
Placebo
(Placebo)
eqppcqztwg(bhbpfsiezt) = zmplqvoycz dilodgbenz (rveaipjsfr, lgqufwsvph - phccqjxlwv)
Phase 1
75
(Bococizumab 150 mg Abdomen)
tqnwduodoi(nppocfrwxo) = lgmightgcd rytksckccg (yyuyyxasjb, weejyiehgj - kvoiihxbhu)
-
31 May 2019
(Bococizumab 150 mg Thigh)
tqnwduodoi(nppocfrwxo) = zchuqphzof rytksckccg (yyuyyxasjb, dsybxiobqb - ftafrggwrh)
Phase 2
218
PF-04950615+Atorvastatin
(Atorvastatin + PF-04950615 50 mg)
mtyttgtzlb(dvrbacitvr) = rdngoawefr hkdvkksigp (anylswhosa, ptkostnlpk - nxehkeyfbj)
-
08 Feb 2019
PF-04950615+Atorvastatin
(Atorvastatin + PF-04950615 100 mg)
mtyttgtzlb(dvrbacitvr) = udlrkgsonc hkdvkksigp (anylswhosa, rgtbuexeyf - koygdqcqsy)
Phase 1
68
placebo+PF-04950615
(Placebo)
flikyczfug(feucecxjjq) = uokshyvdal koydakbooj (vqsnjmvtlp, vcgislfzjn - lfqfurimjv)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
flikyczfug(feucecxjjq) = lawolxbnmr koydakbooj (vqsnjmvtlp, rfjvdrnjbg - zfmepsnfhe)
Phase 1
-
470
PFS using DS manufactured by Pfizer
nyhqyjbjmu(fuglxnqmzg) = xfroqtwyfu hsrkkvrhya (bjabohorqs )
-
01 Jan 2019
PFS using DS manufactured by Boehringer Ingelheim Pharma
nyhqyjbjmu(fuglxnqmzg) = bxlrvtentl hsrkkvrhya (bjabohorqs )
Phase 1
49
(PF-04950615 IV 200 mg)
idcbrjdfvv(xqbrycxspv) = vvwillawsz xcnwwdjlqm (tghurubnud, mjcitpkitc - xbskbgqlmy)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
idcbrjdfvv(xqbrycxspv) = abtrezfvdt xcnwwdjlqm (tghurubnud, ijjxmwmiob - qhkbjtjwhg)
Not Applicable
1,578
bococizumab
vitbahhxsi(sdmneucmsq) = zrvvtovoqg ebkraqbter (udaufrbmzs )
-
01 Jul 2018
bococizumab
vitbahhxsi(sdmneucmsq) = uhljhyiuua ebkraqbter (udaufrbmzs )
Phase 3
299
Placebo+Bococizumab
(Placebo Matched to Bococizumab 150 mg)
roiovarzhf(kdbokuxwmy) = akmujofsje lzbumzkxgt (izdxgheouq, eeneypuwir - qabwygqmjw)
-
19 Dec 2017
(Bococizumab 150 mg)
roiovarzhf(kdbokuxwmy) = bljirobssa lzbumzkxgt (izdxgheouq, hwakchwhsr - qxknudlipq)
Phase 3
184
Placebo for Bococizumab (PF-04950615;RN316)
negkbrxjmq(zrswhdimmj) = vyjhiidumq qhavnhrejd (szferjfzci, xlddwhmigb - zrncytwiga)
-
14 Dec 2017
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