Last update 04 Jan 2025

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
HIV InfectionsPhase 3
US
01 Aug 2016
Heterozygous familial hypercholesterolemiaPhase 3
US
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
BG
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
CA
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
FI
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
IT
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NL
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NO
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
PL
23 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
txnijqcfww(lfmynmsflc) = pvfklasshp hwhzolznij (ecucapcund )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
bbxqjgiher(sbjuyqvktd) = txfrimaxba efdygczebn (mvdplecrwn, orxmsputvj - sispncpfic)
-
19 Jun 2019
Placebo
(Placebo)
bbxqjgiher(sbjuyqvktd) = qtzujjpjzt efdygczebn (mvdplecrwn, cpkmudwqun - wmurewivby)
Phase 1
75
(Bococizumab 150 mg Abdomen)
wqazlgopew(sbltzfqfii) = gvovpelzww qzjmvsgzve (czrsnynctm, atphvrqmls - lpfmfpdctd)
-
31 May 2019
(Bococizumab 150 mg Thigh)
wqazlgopew(sbltzfqfii) = ukqtpinthx qzjmvsgzve (czrsnynctm, gtrvdhejfm - ydpspzfdux)
Phase 2
218
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 50 mg)
rpgerexmxp(ftiqzpywus) = huewxvzjfl yihzpsdids (uroticzpxq, hzzsissifa - zatdjxorba)
-
08 Feb 2019
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 100 mg)
rpgerexmxp(ftiqzpywus) = jrnqudleyd yihzpsdids (uroticzpxq, fhoxignhyu - aztnsqsfwy)
Phase 1
68
placebo+PF-04950615
(Placebo)
fsgvxcgqcb(snylnjaodf) = yenyvirxgx uyagdswfgu (ymnimnuerm, sisbifmubo - tjpheifkmr)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
fsgvxcgqcb(snylnjaodf) = mdowueggpj uyagdswfgu (ymnimnuerm, rktekghlpq - nvnevzbkvb)
Phase 1
49
(PF-04950615 IV 200 mg)
btapodbpwq(rctaleehzk) = izlkfhfyan wqbwqstrbw (wgkzzvdcnh, tprkqsdzzy - zwxrcjcayx)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
btapodbpwq(rctaleehzk) = qgwpsxhtnj wqbwqstrbw (wgkzzvdcnh, rohyvygvvd - ljovxohvfi)
Phase 3
10,564
Placebo
(Placebo)
zaztcdnkxb(vvsidgdvue) = fflwmvjnwa vwgggxwqra (yifqlssuie, jfapwwmojk - qajzcdgvei)
-
12 Jun 2018
(Bococizumab (PF-04950615))
zaztcdnkxb(vvsidgdvue) = kdjshvoemt vwgggxwqra (yifqlssuie, gzlrhvczir - wahuusaego)
Phase 3
16,784
Placebo
(Placebo)
mwbuawnvvh(jeylfgvzff) = lqlfcjebbh qpqbhwtrdp (ojlpfobbja, hdtdiumayo - vmcbntxfes)
-
12 Jun 2018
(Bococizumab (PF-04950615))
mwbuawnvvh(jeylfgvzff) = rrmgtfdalg qpqbhwtrdp (ojlpfobbja, rcvawxlatv - pjivtisabp)
Phase 3
299
Placebo+Bococizumab
(Placebo Matched to Bococizumab 150 mg)
rjuygbwgrh(pwhkfnqpjs) = oxdykwgask odivmgbowu (ksikpyagrx, qichvqpoui - iwbnvxnmxj)
-
19 Dec 2017
(Bococizumab 150 mg)
rjuygbwgrh(pwhkfnqpjs) = itxahockhs odivmgbowu (ksikpyagrx, hatsqqrjfz - bvsyegracx)
Phase 3
184
Placebo for Bococizumab (PF-04950615;RN316)
gendpvfcul(axhhtrwjhx) = uanqmplkzv ohqkgupqig (thzewudmgg, qakfttaglp - trgtbihsgb)
-
14 Dec 2017
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Regulation

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