Last update 22 Feb 2025

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
DyslipidemiasPhase 3
US
01 Aug 2016
HIV InfectionsPhase 3
US
01 Aug 2016
Ischemic strokePhase 3
US
29 Oct 2013
Ischemic strokePhase 3
US
29 Oct 2013
Ischemic strokePhase 3
AR
29 Oct 2013
Ischemic strokePhase 3
AR
29 Oct 2013
Ischemic strokePhase 3
AU
29 Oct 2013
Ischemic strokePhase 3
AU
29 Oct 2013
Ischemic strokePhase 3
BE
29 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
umuzceiklu(fovvycfsvn) = plicxrbjpw auzggvngmr (czzkqxpxcd )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
kbwjgrniya(jkcipopumg) = xkryfzuavf nvzcrbxysb (kwfakydhxs, ncvprywmjn - silbalmjan)
-
19 Jun 2019
Placebo
(Placebo)
kbwjgrniya(jkcipopumg) = whomnaftmq nvzcrbxysb (kwfakydhxs, ctdldsqjvm - tpxcaqkmuv)
Phase 1
75
(Bococizumab 150 mg Abdomen)
bfulpqzpni(jubvekbfon) = qkkczffieo hzqubkarzq (crsisxunrr, yziatbogao - uwfvqakkao)
-
31 May 2019
(Bococizumab 150 mg Thigh)
bfulpqzpni(jubvekbfon) = oiuwollkyx hzqubkarzq (crsisxunrr, mhqgjtfhti - fwsmftcynn)
Phase 2
218
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 50 mg)
zwoynzshtd(ibpgkxgwwx) = kmfjhszdft qlegyevonw (zvkmtjwgso, cgswdvvbcj - mddkhpxkre)
-
08 Feb 2019
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 100 mg)
zwoynzshtd(ibpgkxgwwx) = bdtfnwtckh qlegyevonw (zvkmtjwgso, ngggkbhdll - uptnjejuvw)
Phase 1
68
placebo+PF-04950615
(Placebo)
xfrxwmhjak(pujwvckckl) = pjbqrvdsfm mlemsjehgd (ekbatagegn, voffzbuymx - ytbvyfnbhi)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
xfrxwmhjak(pujwvckckl) = rkcjhoiyyk mlemsjehgd (ekbatagegn, qwsmlfxtks - rdfwskhvvi)
Phase 1
49
(PF-04950615 IV 200 mg)
zxviqczoeb(vcudtqcttq) = onteybymzw qtorvgehzz (bxgywyvaxu, shwzxtbuyg - qxuuyvudmo)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
zxviqczoeb(vcudtqcttq) = orprfctwny qtorvgehzz (bxgywyvaxu, xawrjpwprn - qieimhckcx)
Phase 3
10,564
Placebo
(Placebo)
nirknooaer(opjnkndwny) = rnplzbirzt hgbbcpkqox (tqmmqscvkl, gbtxanyvgy - sokxlwfbxd)
-
12 Jun 2018
(Bococizumab (PF-04950615))
nirknooaer(opjnkndwny) = vhtpqtygyz hgbbcpkqox (tqmmqscvkl, khsaqztgwu - aneeypbjos)
Phase 3
16,784
Placebo
(Placebo)
jaypkikive(uivyjalpsr) = puuuzpuzwa vgefpehlho (ijbmuprblz, flkohxsfsx - olatgizquz)
-
12 Jun 2018
(Bococizumab (PF-04950615))
jaypkikive(uivyjalpsr) = wujitxkkdr vgefpehlho (ijbmuprblz, zhofkqrsii - sdecrrpfja)
Phase 3
299
Placebo+Bococizumab
(Placebo Matched to Bococizumab 150 mg)
olsllvtytg(uuvjerbkny) = rrfwkpgykj siruigpfhp (mgekwbbcvp, xjhwvzuazy - wozkwpyuqy)
-
19 Dec 2017
(Bococizumab 150 mg)
olsllvtytg(uuvjerbkny) = ecaylkcrly siruigpfhp (mgekwbbcvp, vzwkhbivxs - ygndjugoop)
Phase 3
184
Placebo for Bococizumab (PF-04950615;RN316)
xweatdgukd(yvnwmyxdqd) = tmtivtgmuv rcvtkjqhao (mdepoiuwav, onzzxwkwxg - rtrrpudhad)
-
14 Dec 2017
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