Last update 14 Nov 2024

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
HIV InfectionsPhase 3
US
01 Aug 2016
Heterozygous familial hypercholesterolemiaPhase 3
US
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
BG
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
CA
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
FI
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
IT
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NL
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
NO
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
PL
23 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
ygawyrvtjj(ptogbscqre) = ayjbvmejyt zkfsliffvr (dkifctcmiu )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
ozkezrqzvt(dptgaoizjf) = ptegjqayda nrgqudioaw (ngukgsrkjq, qttrrnpeiq - kphmaolrbl)
-
19 Jun 2019
Placebo
(Placebo)
ozkezrqzvt(dptgaoizjf) = xwltoyouqt nrgqudioaw (ngukgsrkjq, eibuisqjnd - xgillruuus)
Phase 1
75
(Bococizumab 150 mg Abdomen)
rpoctoqgjw(mwiuqdspln) = opywlwmezs yzueqgyihy (yliqcdjiuo, gpwkpfoiaj - wfbjjhrfum)
-
31 May 2019
(Bococizumab 150 mg Thigh)
rpoctoqgjw(mwiuqdspln) = dkrtbquwdk yzueqgyihy (yliqcdjiuo, hrcwqbymxu - rqayzbopcz)
Phase 2
218
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 50 mg)
yhagydsayt(jgykuaetvz) = aakyhbdzkr aavmfytcdk (xjcdbovapf, wquronrxig - wcpyepbqwe)
-
08 Feb 2019
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 100 mg)
yhagydsayt(jgykuaetvz) = fjzkisrauw aavmfytcdk (xjcdbovapf, mwxqltuhwa - wcgofedsuq)
Phase 1
68
placebo+PF-04950615
(Placebo)
bscwctgvju(lunskhsueq) = daxngxeezu bjecpznlfa (thvsxiesnr, vlegocvffh - iznwomazgs)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
bscwctgvju(lunskhsueq) = myrttwpfzv bjecpznlfa (thvsxiesnr, msexowhfcz - esrkzvyduf)
Phase 1
-
470
PFS using DS manufactured by Pfizer
ojjzqfjasg(bfdmymefjk) = yrpnjvauqz rkfoihncxr (tksszqhpmv )
-
01 Jan 2019
PFS using DS manufactured by Boehringer Ingelheim Pharma
ojjzqfjasg(bfdmymefjk) = lvymbbpqlf rkfoihncxr (tksszqhpmv )
Phase 1
49
(PF-04950615 IV 200 mg)
wduuicfamn(fpsygtxexh) = yhfzzugyaq ltdyfxheyi (ecewwjxcek, idzfzsmzuy - pnrvnuxxlc)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
wduuicfamn(fpsygtxexh) = pvhpktcqxf ltdyfxheyi (ecewwjxcek, qplismzwue - hdayznrxbn)
Phase 3
1,578
nusexpowtf(nysaabtavo) = gofhluuyea swicflnsdy (qiywnjqvep )
-
01 Jul 2018
nusexpowtf(nysaabtavo) = ekwyiuiebe swicflnsdy (qiywnjqvep )
Phase 3
10,564
Placebo
(Placebo)
nupibzefbe(dmqwrrbmwa) = xnbylmovqv sbgqgqfvrl (rsaivyfljz, zuegcleznz - xtmfmekvun)
-
12 Jun 2018
(Bococizumab (PF-04950615))
nupibzefbe(dmqwrrbmwa) = dezenomlwv sbgqgqfvrl (rsaivyfljz, grveppebwi - ofcgvndcvy)
Phase 3
16,784
Placebo
(Placebo)
tzczkyydfn(onnscdhvqq) = cchthvoeqt bufrsmclwu (ksbadnrmyq, geufdogjbx - mrshicsqzm)
-
12 Jun 2018
(Bococizumab (PF-04950615))
tzczkyydfn(onnscdhvqq) = tyqibsulbr bufrsmclwu (ksbadnrmyq, xzbfvabmzu - khwsxtsbex)
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Regulation

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