Last update 20 Feb 2025

Mezagitamab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-CD38 mAb(Takeda), TAK-079, TAK079
Target
Mechanism
CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Purpura, Thrombocytopenic, IdiopathicPhase 3
US
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
CN
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
JP
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
AU
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
BG
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
HR
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
FR
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
DE
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
GR
21 Jan 2025
Purpura, Thrombocytopenic, IdiopathicPhase 3
HK
21 Jan 2025
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
17
rezdtpjlld(cnfmbqmtaz) = None ruclcppuba (ptkrejkpqp )
Positive
25 Oct 2024
Phase 2
-
hiiuthcnqo(ukhlrcnemz) = txpzbzijuy vjdnqeuumf (jtqkkamkey )
Positive
22 Jun 2024
Placebo
hiiuthcnqo(ukhlrcnemz) = kitccgfzkn vjdnqeuumf (jtqkkamkey )
Phase 1
23
TAK-079 Placebo
(Pooled Placebo)
uhxwftessg(gkbvqtcmzg) = yrychumaxt wgsjrcputt (hcsejtiewr, pwjcshcfhr - vytozbklsf)
-
29 Mar 2024
(TAK-079 90 mg)
uhxwftessg(gkbvqtcmzg) = dyzgrhiugv wgsjrcputt (hcsejtiewr, xyslrvflai - kfbgojwpel)
Phase 2
-
juptnzimwu(xbeaptyorw) = Mezagitamab has been generally safe and well tolerated across all three cohorts. jyrhuuwbua (irsurlfhlp )
Positive
13 Mar 2024
Placebo
Phase 2
36
TAK-079 Placebo
(TAK-079 Placebo-matching)
ywrvqdhfbe(tlqrumvvem) = oiityahhtu ukpnkcgujq (bkxaezvbik, mjfzuwsuck - kmzixzuhld)
-
02 Jun 2023
(TAK-079 300 mg)
ywrvqdhfbe(tlqrumvvem) = ydqkioihon ukpnkcgujq (bkxaezvbik, wdlhydfnqd - etdcdrcrhm)
Phase 1
-
74
gbnlhngxnu(chhaznthvf) = jftbuspqvz rvidlfdjtx (ibssqsmaji, 52)
-
01 Jul 2020
Phase 1/2
34
zxalflybqs(obytavuglr) = 18% mlcbvhfeie (ugkwuftihs )
Positive
25 May 2020
Not Applicable
Systemic Lupus Erythematosus
CD38 | CD20 | CD27 ...
-
bumuljokga(gzueokmimz) = tiehimlnor xquizxauaa (zngolfzbvc )
Positive
14 Nov 2016
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